Enzymes and Inhibitors
Cayman Chemical N-Oleoyl-DPPEamonIum salt 10mg
An N-acyl-phosphatidylethanolamine; a biosynthetic precursor to OEA
Amsbio LLC Heparinase III (Heparitinase I) Flavobacterium heparinum (EC 4.2.2.8), 0.1 IU
Heparinase III (Heparitinase I) Flavobacterium heparinum (EC 4.2.2.8) 0.1 IU
Supply Solutions Liberase™ TL Research Grade, pkg of 10 mg (2x5 mg)
The most commonly used method for decellularization procedures, such as tissue dissociation and cell harvesting, is based on the use of proteolytic enzymes. Proteases disrupt the extracellular matrix of tissue to allow the release of individual cells or the harvesting of cultured cells for transfer. The goal of cell isolation is to maximize the yield of dissociated cells that are viable and functionally active.
Medchemexpress LLC Tlr4-in-c34-c2-cooh | 1159408-54-4 | MFCD30802159 | 99.9% | 447.43 g/mol | C19H29NO11 | 100 MG
TLR4-IN-C34-C2-COOH is a small-molecule PROTAC linker that incorporates a TLR4 inhibitor moiety and is supplied for research use to support studies of TLR4 biology and probe or degrader synthesis. It has documented activity inhibiting TLR4 in enterocytes and macrophages and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
- High purity of 99.9%.
- Molecular formula C19H29NO11; molecular weight 447.43 g/mol.
- Soluble in DMSO and water at 100 mg/mL with ultrasonic assistance.
- Formulation examples yield ≥ 2.5 mg/mL (5.59 mM) in common in vivo vehicles.
- Available in multiple pack sizes including 100 mg.
- Intended for research use only; not for human or veterinary use.
Cayman Chemical Lysosomal ACD LIpase ActIvIt
Cayman's LAL Activity MaxSpec Assay Kit includes the necessary reagents to quantify lysosomal acid lipase (LAL) activity in dried blood spots. The LAL Activity MaxSpec Assay Substrate (P-PMHC) has been designed to function as a highly selective substrate for LAL, which hydrolyzes the fatty acyl group of P-PMHC resulting in the formation of the LAL Activity MaxSpec Assay Product 4-propyl-8-methyl-7-hydroxycoumarin (PMHC). Using the LAL Activity MaxSpec Assay Kit, LAL activity may be quantified directly by fluorometry or by LC-MS in combination with the LAL Activity MaxSpec Assay Internal Standard.
Apexbio Technology LLC EZ Cap OVA mRNA (5-moUTP) 5x1mg (1mg/mL)
Ovalbumin (OVA) mRNA encodes a egg white glycoprotein with a molecular weight of approximately 45 000 daltons It can induce moderate immunogenicity in organisms and is commonly used as an immunogen in immunological experiments such as establishing animal models for hypersensitivity asthma etc EZ Cap OVA mRNA (5-moUTP) is provided at 1 mg/mL capped by co-transcriptional capping with a Cap 1 structure and polyadenylated Modified 5-moUTP incorporation reduces the host cell immune response and enhances mRNA stability and translation efficiency
ABclonal Technology RNase A (10 mg/mL)
Ribonuclease A (RNase A), molecular weight 13.7 kDa, is an endonuclease that specifically acts on the 3 end of the pyrimidine residue on RNA, cleaving phosphodiester bonds formed with adjacent nucleotides, and the final product of the reaction is pyrimidine 3 phosphate and an oligonucleotide with pyrimidine 3 phosphate at the end. RNase A does not work on DNA. This product is DNase and protease free, and it can be used without heat treatment before use. This product is provided in a solution form at a concentration of 10 mg/mL. The recommended working concentration is 1-100 μg/mL, which varies depending on specific applications.
New England Biolabs, Inc. Thymine-DNA Glycosylase (TDG)-500 units
Thymine-DNA glycosylase (TDG) catalyzes the hydrolysis of the N-glycosidic bond of thymine or uracil mispairs opposite guanine that arise from spontaneous deamination events of 5-methylcytosine (5mC) and cytosine, respectively.The excision of the mispaired thymine or uracil base leaves an abasic (AP) site that can then be chemically or enzymatically cleaved.
- Active on dsDNA
- Monofunctional glycosylase that removes dT or dU nucleobases mispaired with dG to create an AP site
- Removes 5-formylcytosine, 5-carboxylcytosine, 5-hydroxymethyluracil, ethenocytosine, 5-fluorouracilIsolated from a recombinant source
- Supplied with 10X TDG Reaction Buffer
Sigma Aldrich Fine Chemicals Biosciences T4 DNA Ligase recombinant
T4 DNA Ligase catalyzes the formation of phosphodiester bonds between neighboring 3-hydroxyl- and 5-phosphate ends in double-stranded DNA. Single-stranded nicks in double-stranded DNA are also closed by T4 DNA Ligase.ContentsT4 DNA Ligase supplied with 10x concentrated ligation buffer that includes ATP.
Discovery Life Sciences HUM CYP2A6+REDUCTASE+B5 0.5NMO
Human CYP2A6 + P450 Reductase + Cytochrome b5 SUPERSOMES 0.5 nmole cytochrome P450 in 0.5mL This activity is catalyzed by CYP2A6 expressed from human CYP2A6 cDNA using a baculovirus expression system
Discovery Life Sciences POOLED MALE DOG LIVER (BEAGLE)
BD Gentest, Pooled Male Dog Liver Microsomes (Beagle), Regulatory Status: RUO
Discovery Life Sciences HUMAN P450 OXIDOREDUCTASE+B5
BD Gentest, Human P450 Oxidoreductase + b5 Insect Control, Regulatory Status is RUO