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Casein kinase inhibitor A86 is a potent small-molecule inhibitor of casein kinase 1α (CK1α) with reported activity against CDK7 and CDK9. Supplied as a 10 mM solution in DMSO, it is intended for biochemical and cell-based research applications, including studies of apoptosis and leukemia-related signaling pathways.
Potent CK1α inhibitor with activity against CDK7 and CDK9.
Supplied as a 10 mM solution in DMSO for ready use in assays.
High purity suitable for research: 99.3%.
Molecular formula C18H25FN6; molecular weight 344.43 g/mol.
Volume 1 mL, convenient for small-scale experiments.
For research use only; not for human therapeutic applications.
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Pyruvate Kinase (PK) is a glycolysis enzyme and has four isozymes L R M1 and M2. The L isozyme is localized in gluconeogenic tissues particularly in the liver. Whereas the R and M1 are localized in the adult skeletal muscles heart brain and erythrocytes respectively. M2 is localized in the nucleus of the cells.
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Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Casein kinase 1(delta)-IN-1 (WAY-643895) is an inhibitor of casein kinase 1(delta) (CK1(delta)) which inhibits CK1(delta). Casein kinase 1(delta)-IN-1 can be used in the study of neurodegenerative diseases such as Alzheimer's disease. purity: 99%
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