Modifying Enzymes
American Research Products Inc BoVine DeoXyribonuclease 1 DN
BoVine DeoXyribonuclease-1 (DNASE1) ELISA kit from CUSABIO Detection Range 12 5 pg/mL-800 pg/mL Sensitivity 3 1 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Medchemexpress LLC DNA Ligase IV antibody (YA2699) | 10 UL
DNA Ligase IV antibody (YA2699) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets DNA Ligase IV. This antibody plays a critical role in DNA non-homologous end joining (NHEJ), specifically in double-strand break (DSB) repair and V(D)J recombination, by catalyzing the NHEJ ligation step to reseal DNA breaks.
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated
- Targets DNA Ligase IV
- Reactivity: Human
- Application: WB (Western Blot)
- Dilution ratio: 1:500-1:1000 for WB
- SwissProt ID: P49917
- Research field: Epigenetics and nuclear signaling
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Appearance: Liquid
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
INTACT GENOMICS INC Endonuclease IV (Nfo) 2000 Units (10 units/µl)
Endonuclease IV (Nfo) from Escherichia coli is a 32-kD metalloprotein that aids in the repair of damaged DNA. The enzyme functions both as an apurinic/apyrimidinic nuclease (1) and as a 3′-terminal di-esterase (1-4). Its 3′-terminal di-esterase activity is important in the repair of DNA strand breaks generated by oxidation and ionic radiation (2, 3). In such events, the strand breaks terminate with either a 3′ phosphate or a deoxyribose fragment, preventing repair by DNA polymerase I or DNA ligase. Endonuclease IV removes the blocking groups, leaving a free 3′-hydroxyl terminus. This enzyme does not have detectable associated exonuclease or DNA N-glycosylase activity (1).Applications• Single cell gel electrophoresis (Comet assay) (5, 6)• Alkaline elution (7)• Alkaline unwinding (8)Product SourceE. coli BL21 (DE3) strain expressing E. coli Endonuclease IV gene.Product Includes• Endonuclease IV (Nfo)• 10x Endonuclease IV reaction buffer
Medchemexpress LLC α-Amylase, human pancreas | 9000-90-2 | 100 U
α-Amylase, Human Pancreas (Amylase) is a hydrolase enzyme that can be isolated from human pancreas. It catalyzes the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. It can be used in life science research.
- Can be used in the study of starch metabolism.
- Suitable for laboratory centrifugation and storage.
Medchemexpress LLC α-Amylase-IN-3 | 93944-58-2 | 99.5% | 267.24 | 1 ML
α-Amylase-IN-3 (Compound 4) is an inhibitor for α-Amylase, AChE, and BChE, with respective IC50 values of 18.04 μM, 21.04 μM, and 22.2 μM. It demonstrates antioxidant activity and is utilized in research concerning diabetes and oxidative stress-associated diseases. The product is supplied as a white to off-white solid.
- Inhibits α-Amylase, AChE, and BChE
- Exhibits antioxidant activity, scavenging free radicals DPPH and ABTS
- Suitable for research on diabetes and oxidative stress-associated diseases
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage for solution: -80°C for 6 months, -20°C for 1 month
- Aliquot and store stock solutions to prevent inactivation from repeated freeze-thaw cycles
- For research use only
Bioworld DNase I (Bovine Pancreas), 100 KU
DNase I DNase I is an endonuclease derived from bovine pancreas that will degrade double-stranded DNA in the presence of divalent cations, producing 3'-OH oligonucleotides. Mg+2 in the reaction solution causes the enzyme to produce nicks in double-stranded DNA, while in the presence on Mn+2, DNase I cleaves both strands of the DNA. DNase I is useful in nick translation for introducing single-stranded nicks that serve as primer sites for initiation of DNA synthesis and for cloning random DNA fragments by cleaving double-stranded DNA. It is also used in purifying RNA from cells or transcription mixtures. Specifications:CAS: 9003-98-9EC: 232-667-0Source: Bovine pancreasActivity: ≥10000 U/mg.Ultra Pure GradeOur DNase I is guaranteed free of RNase contaminants.
INTACT GENOMICS INC Cas9 Nuclease 40 µg
Intact Genomics Cas9 Nuclease is the purified recombinant Streptococcus pyogenes Cas9 enzyme containing a nuclear localization signal (NLS) at the C-terminal for targeting to the nucleus. This enzyme is designed to perform CRISPR/Cas9-mediated genome editing (1, 2). The physical purity of this enzyme is ≥98% as assessed by SDS-PAGE with Coomassie blue staining. Product Source:E. coli BL21 (DE3) strain expressing a Cas9 gene from Streptococcus pyogenes with an N-terminal 6xHis tag and C-terminal SV40 nuclear localization signal (NLS).Product Includes: Cas9 Nuclease 10x Cas9 Nuclease Reaction Buffer
Apexbio Technology LLC EZ Cap OVA mRNA (m1Ψ) 5x1mg (1mg/mL)
Ovalbumin (OVA) mRNA encodes a egg white glycoprotein with a molecular weight of approximately 45 000 daltons It can induce moderate immunogenicity in organisms and is commonly used as an immunogen in immunological experiments such as establishing animal models for hypersensitivity asthma etc EZ Cap OVA mRNA (m1 ) is provided at 1 mg/mL capped by co-transcriptional capping with a Cap 1 structure and polyadenylated Modified m1 incorporation reduces the host cell immune response and enhances mRNA stability and translation efficiency
Bioss KD-Validated Coenzyme A syntha
Coenzyme A Synthase Primary Antibody Unconjugated Public Immunogen Range 530-564/564 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ABclonal Technology PNGase F, Recombinant (Expressed in E.coli)
Peptide N-glycosidase F (PNGase F) is a glycosylpeptidase with a theoretical molecular weight of 35.9 kD that can cleave asparagine-linked high mannose, hybrid, and complex oligosaccharides from glycoproteins. PNGase F cleaves the amide bond between innermost N-acetylglucosamine (GlcNAc) and asparagine residues of the glycoprotein, converting asparagine to aspartic acid in the process. This product is commonly used for the deglycosylation of antibodies and glycoproteins.
Carbosynth LLC. 5-Bromo-4-chloro-3-indoxyl-beta-D-glucuronic acid, cyclohexylammonium salt monohydrate, 114162-64-0, MFCD00058543, 1 g
Formula: C20H28BrClN2O8, Molecular weight: 539.81 g/mol, 99%, Store at -15°C, Synonyms: X-beta-D-glucuronide cyclohexylammonium salt; X-beta-D-glucuronide CHX-salt; X-beta-D-GlcA · CHX.
Biotium CD45 / LCA (Leucocyte Marker)(Bra55), CF568 conjugate, 0.1mg/mL
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Cayman Chemical 18hydroxy Oleoyl LeucInd7 1mg
An internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS