General Clinical Chemistry Analyzers and Accessories
AdipoGen 3-oxo-C8-L-HSL
Chemical. CAS 147795-39-9. Formula C12H19NO4. MW 241.3. Synthetic. N-3-Oxooctanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. This compound stimulates the tra gene expression. It is an autoinducer and potent antagonist. Promotes the expression of the transcriptional activator and LuxR homolog TraR, in the gram-negative bacterium A. tumefaciens.
Abcam LRRK2-IN-1, LRRK2 inhibitor, 10MG
MW 570.7 Da. Potent and selective inhibitor of the Parkinson's disease kinase LRRK2. Benzodiazepine based derivative. Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC₅₀ values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2. Inhibits IFN-γ-induced monocyte maturation in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Alkali Scientific 5mL False Bottom Analyzer Tubes with Threads, 16×97mm, Polypropylene (PP), Amber, 1000/Pk
These 5mL False Bottom Analyzer Tubes (16×97mm) with Threads are designed for use in high volume chemistry and diagnostic analyzers. They are compatible with popular analyzers from Hitachi, Olympus, Corning, Ortho, Kodak, Beckman, IA, Tosoh, Vitros and more. Manufactured from high grade polypropylene (PP), these tubes offer excellent chemical resistance and can be safely autoclaved at 121 °C. With a conical false bottom for reduced dead volume and accurate sample retrieval, these tubes are ideal for serum collection, sample transport, or storage. Available in natural or amber options to protect light sensitive samples, they are self standing and designed to fit most universal analyzer racks, including AU 5000 systems. Features: 5mL nominal capacity, 16×97 mm Compatible with Hitachi, Olympus, Corning, Ortho, Beckman, Vitros, Tosoh, and other analyzers Made of chemical resistant polypropylene; autoclavable at 121 °C Available in natural or amber PP for light sensitific.
Abcam 7-Cl-O-Nec1, metabolically stable RIP1 inhibitor, 5MG
MW 277.7 Da, Purity >98%. Necrostatin-1 (ab141053) analog with superior selectivity and metabolic stability in blocking RIP1. No off-target inhibition of indolamine-2,3-deoxygenase (IDO) in contrast to Necrostatin-1. Higher activity in inhibiting necroptosis in Jurkat cells than Necrostatin-1 (EC₅₀ = 210 nM vs. EC₅₀ = 490 nM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam ABT-199 (Venetocla x ), Bcl-2 inhibitor., 1MG
MW 868.4 Da, Purity >98%. Potent, selective Bcl-2 inhibitor (Ki <0.01 nM) that inhibits the growth of Bcl-2–dependent tumors while sparing platelets. Bcl-2–specific BH3 mimetic. Promising agent in the treatment of chronic lymphocytic leukaemic and estrogen receptor-positive breast cancer.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ML-385, 25MG
MW 511.6 Da, Purity >=98%. A potent and selective Nrf2 inhibitor (Nrf2; IC₅₀ = 1.9 μM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Cefpodoxime
Chemical. CAS 80210-62-4. Formula C15H17N5O6S2. MW 427.46. Synthetic. Cefpodoxime is a metabolite of cefpodoxime proxetil, an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria MIC90 ranges from 0.015-8 µg/ml. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls.
AdipoGen Ohira-Bestmann Reagent
Chemical. CAS 90965-06-3. Formula C5H9N2O4P. MW 192.11. Synthetic. Used in the Seyferth-Gilbert homologation which is a chemical reaction of an aryl ketone or aldehyde with dimethyl- or diazomethyl-phosphonate and potassium tert-butoxide to give substituted alkynes.
AdipoGen Etobenzanid
Chemical. CAS 79540-50-4. Formula C16H15Cl2NO3. MW 340.2. Synthetic. Herbicide. Compound can be used as analytical reference material.
Abcam Indo x imod, Indoleamine 2,3-dio x ygenase (IDO) inhibitor, 500MG
MW 218.25 Da, Purity >95%. Methylated tryptophan which acts as an Indoleamine 2,3-dioxygenase (IDO) inhibitor. Prevents T-cell anergy triggered by dendritic cells overexpressing IDO in mice.
The product is subject to the following: Abcam Restricted Use Statement
(CCCC)C#C[Si](C)(C)C | 5g | 525924538](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696479.jpg-250.jpg)
eMolecules 81353-38-0 | Trimethyl(2-tributylstannylethynyl)silane | Synthonix - Stock | MFCD03844806 | 387.270 | C17H36SiSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C#C[Si](C)(C)C | 5g | 525924538
Trimethyl(2-tributylstannylethynyl)silane | Synthonix - Stock | 81353-38-0 | MFCD03844806 | 387.270 | C17H36SiSn | 95.000 | CCCC[Sn](CCCC)(CCCC)C#C[Si](C)(C)C | 5g | 525924538
AdipoGen 3OH-C12-DL-HSL
Chemical. CAS 182359-60-0. Formula C16H29NO4. MW 299.41. Synthetic. Quorum sensing agent.
AdipoGen Monosultap
Chemical. CAS 29547-00-0. Formula C5H12NNaO6S4. MW 333.4. Synthetic. Nereistoxin analog insecticide. Insect nicotinic acetylcholine receptors nAChRs channel blocker. Compound can be used as analytical reference material.
Arizona Instrument LLC Flat Sample Pans for Computrac® MAX® 4000XL, 100/pk
This item has a minimum qty of 3 per supplier requirements.
Flat Sample Pans 100/pk.
Abcam AZ-20, 25MG
MW 412.5 Da. Potent and selective ATR kinase inhibitor (IC₅₀ = 5 nM in vitro; IC₅₀ = 50 nM in carcinoma cell lines). Selective versus mTOR (8-fold). Displayed selectivity versus a panel of 442 kinases.Inhibits LoVo colorectal adenocarcinoma tumor cell growth.
The product is subject to the following: Abcam Restricted Use Statement