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Ubiquitin Derivatives – Ubiquitin Aldehyde (UBPBio catalog# F3100) – Ub aldehyde is a potent and highly specific inhibitor of cysteine deubiquitinating enzymes including the Ub C-terminal hydrolases (UCHs), the Ub-specific proteases (USPs), the ovarian tumor domains (OTUs) proteases and the Machado-Josephine domain (MJD) proteases. Typical working concentration is 2-5 µM in vitro.
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Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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AZD8330 (ARRY704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Pazopanib HCl is a novel multi-target inhibitor of VEGFR1 VEGFR2 VEGFR3 PDGFR FGFR c-Kit and c-Fms with IC50 of 10 nM 30 nM 47 nM 84 nM 74 nM 140 nM and 146 nM in cell-free assays respectively Pazopanib induces autophagic Type II cell death
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Defosbarasertib (AZD1152-HQPA AZD2811 INH-34 Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0 37 nM in a cell-free assay 3700 fold more selective for Aurora B over Aurora A Phase 1
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Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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