Custom Peptides
Cayman Chemical SynthetIc OmbuIn 10mg
A flavonoid with diverse biological activities; an antagonist of M1 mAChRs (Ki = 42 µM in CHO-K1 cells expressing the human receptor); cytotoxic to HepG2 cancer cells (IC50 = 1.5 UG/ml); reduces blood urea and glucose levels, urinary volume and protein levels, serum creatinine levels, renal fibrosis levels, and body weight in a rat model of STZ-induced diabetic nephropathy at 40 mg/kg per day
Cayman Chemical AposcopolamIn 10mg
A tropane alkaloid and an active metabolite of scopolamine; selective for mAChRs over nAChRs (IC50s = 0.0192 and 188 µM, respectively)
Cayman Chemical GentIopIcrIn 10mg
An iridoid glycoside with diverse biological activities; attenuates ANIT-induced acute cholestasis and liver damage and reverses bile acid dyshomeostasis in mice at 130 mg/kg; increases the paw withdrawal threshold in the cold-plate test and latency to paw withdrawal in the plantar test in mice at 25, 50, and 100 mg/kg; decreases NMDA receptor-mediated EPSCs in the nucleus accumbens and reverses morphine-induced conditioned place preference in mice at 100 mg/kg
Cayman Chemical SynthetIc Aurapten 10mg
A coumarin derived from citrus plants with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities; inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis
Cayman Chemical 13 14dIhydro15 RProstagla 10mg
13,14-dihydro-15(R)-PGE1 is an analog of 13,14-dihydro-PGE1, which has the hydroxyl group at C-15 in the unnatural R configuration.
Cayman Chemical 5-trns ProstaglndIn F2atr 10mg
5-trans PGF2α tromethamine salt is a derivative of 5-trans PGF2α with increased water solubility. Its solubility in PBS is 25 mg/ml compared to 10 mg/ml for 5-trans PGF2α.
Cayman Chemical 1PalmItoyl2LInoleoyl3Ste 10mg
A triacylglycerol; has been found in mature human milk and various plant oils
Cayman Chemical Alntus altsma Alnton 10mg
A quassinoid with diverse biological activities; active against the P. falciparum strains HB-3 and Dd-2 in vitro (IC50s = 0.003 and 0.037 μg/ml, respectively); inhibits radish seed germination by 88% when used at a concentration of 1 mM; inhibits dihydrotestosterone-induced androgen receptor transcriptional activity (IC50 = 69 nM in a reporter assay), as well as the growth and colony formation of LNCaP and 22RV1 cells at 0.1 μM; reduces tumor volume in 22Rv1, LNCaP, and VCaP CRPC mouse xenograft models at 2 mg/kg
Cayman Chemical DmyoInosItol1phosphatec 10mg
A member of the inositol phosphate molecular family of second messengers that play critical roles in intracellular signaling
Cayman Chemical EchInacosIde 10mg
A phenylethanoid glycoside; scavenges DPPH radicals (EC50 = 6.6 µM in a cell-free assay); inhibits hydrogen peroxide-induced production of ROS in a cell-free assay at 10 UG/ml; reduces increases in plasma ALT, TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury at 60 mg/kg; prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and DOPAC levels in a mouse model of MPTP-induced Parkinson's disease; improves motor performance in the rotarod test in the same model
Cayman Chemical Chromn 1hydrochLRIde hydr 10mg
A ROCK2 inhibitor (IC50 = 50s = 1,740 and 127 nM, respectively); inhibits phosphorylation of MLC in a cell-based assay (IC50 = <4 nM)
Cayman Chemical SAAP 148trIfluoROCTAte sa 10mg
An antimicrobial peptide; active against several multidrug-resistant bacteria in vitro; decreases the number of skin CFUs in mouse models of A. baumannii or MRSA infections at 0.125-2% w/w
Cayman Chemical Decnoyl m-NItronIlIn 10mg
One of several nitroaniline fatty acid amides that can be used to measure FAAH activity; exposure to FAAH results in the release of the yellow colorimetric dye m-nitroaniline (ε = 13,500 at 410 nm) allowing for fast and convenient measurement of FAAH activity using a 96-well plate spectrophotometer
Cayman Chemical AcetoxyvalerenIc AcId 10mg
A sesquiterpenic acid; cytotoxic to GLC-4 and COLO 320 cells (IC50s = 111 and 124 µM, respectively)