Custom Peptides
Cayman Chemical Esmolol-d7hydrochlorIde 10mg
An internal standard for the quantification of esmolol by GC- or LC-MS
Cayman Chemical SchIsnhenol 10mg
A lignan with diverse biological activities; completely inhibits iron and cysteine-induced MDA formation in rat liver microsomes at 1 mM; reduces HIV-1 viral titers in H9 T cells (EC50 = 5.7 µM); protective against tobacco mosaic virus (TMV) infection in N. glutinosa when applied to leaves from 0.15-0.5 mM; prevents scopolamine-induced increases in hippocampal MDA and AChE levels and decreases hippocampal SOD and GPX activities, as well as increases time spent in the target quadrant in the Morris water maze in mice at 10, 30, or 100 mg/kg
Cayman Chemical AdenylosuccInIc AcId 10mg
A purine nucleotide and an intermediate in the purine nucleotide cycle; converted into AMP and fumarate by ADSL in the cytosol; inhibits calcium-induced activation of non-selective cation channels in isolated rat brown adipocytes in a patch-clamp assay at 10 µM; induces contractions in isolated guinea pig uterus strips at 100 µM; increases glucose-induced insulin exocytosis in INS-1 832/13 insulinoma cells at 10 µM; decreases muscle damage and pseudohypertrophy in a dystrophin-deficient mdx mouse model of DMD
Cayman Chemical 5-trns ProstaglndIn F2atr 10mg
5-trans PGF2α tromethamine salt is a derivative of 5-trans PGF2α with increased water solubility. Its solubility in PBS is 25 mg/ml compared to 10 mg/ml for 5-trans PGF2α.
Cayman Chemical NVS-CECR2-1 10mg
A potent and selective inhibitor of CECR2 (IC50 = 0.047 µM by Alpha screen, Kd = 0.80 µM by ITC); shows robust activity in cells, by FRAP assay, due to its slow off-rate
Cayman Chemical AltIratInIb 10mg
A multiple kinase inhibitor, blocking Met, Tie2, VEGF2, TrkA, TrkB, and TrkC with IC50 values of 2.7, 8.0, 9.2, 0.85, 4.6, and 0.83 nM, respectively; orally bioavailable and penetrates the blood brain barrier, suppressing the growth of subcutaneous and intracerebroventricular xenograft tumors in mice
Cayman Chemical XnthosIn 5-monphosphate 10mg
An intermediate in purine metabolism, the product of the rate limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis.
Cayman Chemical CurcumaZerumbon 10mg
A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM); inhibits SHH signaling and induces apoptosis in cancer cell lines
Cayman Chemical p-APMSFhydrochlorIde 10mg
An irreversible inhibitor of serine proteases (Kis = 1.02, 1.18, 1.5, and 1.54 µM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively); selective for these proteases over bovine chymotrypsin and acetylcholinesterase
Cayman Chemical RPramIpexolehydrochLRId 10mg
An enantiomer of pramipexole that is ~100-fold less active than the (S) form as a dopamine receptor agonist; an antioxidant that targets mitochondria to prevent apoptosis
Cayman Chemical ZofenoprIlcalcIum salt 10mg
A prodrug form of zofenoprilat; an ACE inhibitor (IC50 = 0.9 nM in heart tissue homogenates); reduces mean arterial blood pressure in 2K-1C rats and SHRs at 2.2, 6.6, and 22 mg/kg
Perkin Elmer US LLC Custom Standard HI 1A, 500 mL
Al @ 10 µg/mL, Mg @ 20 µg/mL Ca @ 32 µg/mL Cu, Fe, Pb, Zn @ 50 µg/mL B @ 1000 µg/mL, P @2000 µg/mL K @ 5000 µg/mL Na @10,000 µg/mL Matrix: 3% HNO3 (v/v) Volume: 500 mL
Cayman Chemical 1 2DIphytnoylsnglycero3 10mg
A phospholipid containing the tetramethylated long-chain (16:0) diphytanic acid inserted at the sn-1 and sn-2 positions
Cayman Chemical L-Alanosine 10mg
An inhibitor of adenylosuccinate synthase (mean IC50 = 4.8 μM and 10 μM in T-ALL and CAK-1 cells, respectively); antineoplastic activity in MTAP deficient cells; disrupts de novo purine biosynthesis and inhibits cellular metabolism
Cayman Chemical AcalabrutInIb 10mg
An irreversible BTK inhibitor; dose-dependently inhibits B cell receptor signaling in primary CLL cells