Custom Peptides
Cayman Chemical FluphenazInN2chLRoethn 10mg
A conjugated PUFA that induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 1-5 UM) increases the production of ROS leading to oxidative stress that contributes to cytotoxicity
Cayman Chemical RS 102895hydrochlorIde 10mg
Immunogen Purified sheep seminal vesicular COX-1 Host Rabbit Species Reactivity ( ) Murine COX-1 sheep seminal vesicular COX-1 sheep placental COX-2 Applications WB
Cayman Chemical YS-035hydrochlorIde 10mg
mPPARa Reporter Cells are prepared using INDIGOs proprietary CryoMite process. This cryo-preservation method yields high cell viability post-thaw and provides the convenience of immediately dispensing healthy division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps viability determinations or cell titer adjustments. [INDIGO Catalog Nos. M00111-32 M00111]
Cayman Chemical EnalaprIlathydrate 10mg
A mixture of ganglioside GD1a with C181 and C201 sphingoid backbones found in brain erythrocytes bone marrow testis spleen and liver can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation invasion and metastasis increases endothelial cell proliferation acts as a functional coreceptor for TLR2
Cayman Chemical ArachIdonyl ChlorIde 10mg
The major secretory product of adrenal glands and the predominant circulating precursor for active steroid hormones in humans used as a biomarker in some adrenocortical disorders
Cayman Chemical 8bromo CyclIc GMPsodIM sa 10mg
A sterol-derived hormone that acts as a ligand of DAF-12 (EC50 23 nM 50 nM inhibits the dauer-promoting activity of DAF-12 blocking the formation of infective larvae in several parasitic nematodes in favor of reproductive maturation to adults
Cayman Chemical ProstaglndIn F2a mthyl St 10mg
An ENaC blocker that inhibits sodium transport from (IC50 4 nM) and binds to (Kd 5 nM) bovine kidney cortex membrane vesicles an NCX blocker that inhibits the cytosolic calcium response to extracellular sodium depletion in mouse podocytes (IC50 ~ 100 nM) an inhibitor of TRPP3 (IC50 1.1 M)
Cayman Chemical 3 4-EDMAhydrochlorIde 10mg
An indolylmaleimide derivative which at 1 M inhibits necrotic cell death induced by H2O2 in HL-60 cells does not prevent etoposide-induced apoptosis or inhibit PKC or S6K1
Cayman Chemical RItalInIc AcId 10mg
A potent cell-permeable mimetic of BH3 domains that avidly binds Bcl-2 Bcl-xL and Bcl-W (Ki death proteins leading to apoptosis
Cayman Chemical 2SOctylahydroxyglutarate 10mg
A non-selective bromodomain inhibitor that at 1 UM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells
Cayman Chemical 6-keto ProstaglndIn F1a 10mg
A microbial metabolite that binds the TCR on VY9V2 peripheral blood lymphocytes with high affinity (EC50 0.39 nM) induces the expansion of human memory VY9V2 T cells
Cayman Chemical ChlorthalIdon 10mg
An analytical reference standard categorized as a tryptamine induces the HTR in mice substitutes for DOM in a two-lever drug discrimination test in rats intended for research and forensic applications
Cayman Chemical Zaltoprofen 10mg
A minor tobacco alkaloid an agonist of a4B2 and a6/a3B2B4 subunit-containing nAChRs (EC50s 6.1 and 3.6 UM respectively) selective for these nAChRs over a3B4 subunit-containing nAChRs or a7 nAChRs (EC50s 70.6 and 158.5 UM respectively) stimulates dopamine release from isolated rat brain synaptosomes (EC50s 1.76 and 100 UM respectively) has anxiolytic-like activity in zebrafish at 10 mg/L decreases disease severity in a mouse model of thyroglobulin CFA and M. tuberculosis immunization-induced moderate experimental autoimmune thyroiditis decreases food and nicotine self-administration in monkeys (ED50s 2.085 and 0.854 mg/kg respectively) has been used as a biomarker of tobacco use