Custom Peptides
Cayman Chemical CIcloprofen 10mg
An NSAID; inhibits ragweed-, A23187-, or concanavalin A-induced histamine release in isolated human leukocytes at 0.5 mM; inhibits carrageenan-induced paw edema in rats (ED50 = 67 mg/kg)
Cayman Chemical GnoderIc AcId G 10mg
A triterpenoid with anticancer and anti-inflammatory activities; inhibits proliferation of Meth A sarcoma cells (IC50 = 6.8 UG/ml); inhibits the production of NO in LPS-induced BV-2 microglial cells (IC50 = 5.77 µM)
Cayman Chemical dmodum styracfolum Vcn2 10mg
A flavonoid glycoside with diverse biological activities; inhibits thrombin-induced aggregation of isolated mouse platelets from 2-30 µM; increases tail bleeding time in mice at 35.7 UG/animal; reduces tumor growth in a PC3 prostate cancer mouse xenograft model at 1 mg/kg; decreases trabecular separation, as well as increases trabecular thickness and area, in an ovariectomized rat model of osteoporosis; decreases ulceration and increases colon weight and length in a mouse model of DSS-induced colitis at 50 mg/kg
Cayman Chemical AlytSIntrIfluoROCTAte sa 10mg
A neuropeptide with diverse biological activities; induces hypertension with tachyphylaxis and increases blood glucose levels in dogs; reduces gastric acid secretion in rats; induces anorexigenic effects in neonatal chicks
Cayman Chemical CarbetocInacetate 10mg
A peptide oxytocin receptor agonist; binds to oxytocin receptors (Kd = 1.96 nM); selectively binds to oxytocin receptors over vasopressin V2 receptors (Kds = 1.96 and 61.3 nM, respectively); induces contraction of isolated rat uterine strips (EC50 = 48 nM); inhibits oxytocin-induced contraction of isolated rat uterine strips (pA2 = 8.21); increases the frequency and amplitude of uterine contractions in EArly postpartum dairy cows at 0.35 mg/animal; prevents stress-induced reinstatement of morphine-seeking behavior in mice at 6.4 mg/kg; reverses learned helplessness and decreases social withdrawal induced by chronic unpredictable stress in tree shrews
Cayman Chemical CytIdIn 3-monphosphate 10mg
A ribonucleotide; produced by hydrolysis of cytidine 2’,3’-cyclic monophosphate via RNase; inhibits RNase; can be dephosphorylated to cytidine by 3’-nucleotidase
Cayman Chemical DelphInIdIn3OrutInosIdec 10mg
A glycosylated anthocyanin with antioxidant activity; inhibits TBHP-induced loss of viability in isolated rat aortic SMCs, but not MH1C1 cells, at 100 µM; prevents TBHP-induced DNA damage, as well as inhibits TBHP-induced increases in MDA levels, in SMCs; displays a hydrogen peroxide-induced and pH-dependent chemiluminescence peak at pH 7
Cayman Chemical O-desethyl DapaglIflozIn 10mg
An SGLT2 inhibitor (IC50 = 9.4 nM) and active metabolite of dapagliflozin; selective for SGLT2 over SGLT1 (IC50 = 970 nM)
Cayman Chemical CastnospermIn 10mg
An inhibitor of both α- and β-glucosidases, inhibiting lysosomal and neutral α-glucosidases with Ki values of 0.1 and 10 μM, respectively, and lysosomal and cytosolic β-glucosidases with Ki values of 7 and 40 μM, respectively; blocks N-linked glycosylation, affecting protein trafficking
Cayman Chemical Fucoxnthn 10mg
A carotenoid that occurs naturally in certain algae; significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet; increases the amount of UCP1 protein in WAT; decreases blood glucose and plasma insulin levels in diabetic mice
Cayman Chemical Lycors radta Ungeremn 10mg
A betaine-type alkaloid with diverse biological activities; an inhibitor of AChE (IC50 = 0.35 µM); a topoisomerase-IIβ poison; inhibits the relaxation of supercoiled DNA by human topoisomerase I and -IIα and E. coli topoisomerase I and -IV (IC50s = 6.1, 25.8, 15, and 7.3 µM, respectively); inhibits the growth of a variety of cancer cells (IC50s = 0.7-2.5 µM); cytotoxic to a variety of drug-sensitive and -resistant cancer cells (IC50s = 4.89-6.45 and 3.67-75.24 µM, respectively); induces ferroptosis, necroptosis, apoptosis, and autophagy in CCRF-CEM leukemia cells; reduces tumor growth in a GXF251L mouse xenograft model at 60 mg/kg twice per week
Cayman Chemical SynthetIc ScoulerIn 10mg
A benzylisoquinoline alkaloid with diverse biological activities; selectively binds to the dopamine D1 and D2 receptors (Kis = 22 and 214 nM, respectively) over 5-HT1A and 5-HT2A receptor subtypes in HEK293 cells at 10 µM; inhibits proliferation in a panel of leukemia cell lines (IC50s = 2.7-6.5 µM); inhibits methamphetamine-induced conditioned place preference in mice at 5 mg/kg