Nucleic Acid Synthesis
Medchemexpress LLC Cyclic-di-GMP disodium | 2222132-40-1 | 98.78% | 734.37 | 100 MG
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates various aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. It exhibits anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be utilized in cancer research.
- Purity: 98.78%
- Appearance: Solid
- Color: Off-white to light yellow
- Initial source: Endogenous metabolite
- Shipping: Shipped with dry ice
- Storage: -80°C, protect from light, stored under nitrogen
Meridian Life Science Hi-throughput dUTP qPCR Lo-ROX, 2500UL
Hi-throughput dUTP qPCR Lo-ROX Mix comprises a master mix containing Taq polymerase, reaction buffer, MgCl2 and optimized dNTP/dUTP mix, PCR enhancers and a passive reference dye. It is designed for stringent amplification of highly-structured and very low copy-number DNA targets, preventing carry-over qPCR contamination, makes Hi-throughput dUTP qPCR lo-ROX ideal for multiplex assays on open, automated, high-throughput instruments.
Meridian Life Science Hi-throughput dUTP qPCR Mix, 1ML
Hi-throughput dUTP qPCR Mix comprises a master mix containing Taq polymerase, reaction buffer, MgCl2 and optimized dNTP/dUTP mix, and PCR enhancers. It is designed for stringent amplification of highly-structured and very low copy-number DNA targets, preventing carry-over qPCR contamination, makes Hi-throughput dUTP qPCR ideal for multiplex assays on open, automated, high-throughput instruments.
Meridian Life Science Hi-throughput dUTP qPCR Mix, 5ML
Hi-throughput dUTP qPCR Mix comprises a master mix containing Taq polymerase, reaction buffer, MgCl2 and optimized dNTP/dUTP mix, and PCR enhancers. It is designed for stringent amplification of highly-structured and very low copy-number DNA targets, preventing carry-over qPCR contamination, makes Hi-throughput dUTP qPCR ideal for multiplex assays on open, automated, high-throughput instruments.
eMolecules 116371-67-6 | Medchem Express | Gemcitabine monophosphate | 1mg | 784543672 | HY-108932 | 343.18 | C9H12F2N3O7P
Medchem Express | WZ4141 | 1mg | 446257884 | HY-103015 | 1222776-76-2 | 279.299 | C16H13N3O2
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Enzo Life Sciences SEEBRIGHT Gold 525 dUTP (lyophilized) (50nmol)
Gold 525 [5(6)-Carboxyrhodamine 6G] dUTP can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase. Fluorescently labeled probes can be prepared with this fluorescent nucleotide by a variety of methods including nick translation, random prime labeling, cDNA labeling and 3’-end labeling. Probes generated by these methods are suitable for use for the identification of specific sequences by in situ hybridization procedures on fixed cells and tissues by direct fluorescence detection. Gold 525 dUTP can also be used for multicolor fluorescence labeling. Alternative name: 5(6)-Carboxyrhodamine 6G dUTP. Quantity: Sufficient for approximately 98 reactions, following the recommended protocol of ENZ-GEN111. Purity: ≥93% (HPLC). Formulation: Lyophilized.
Cayman Chemical N6 N6-DImethyladenosIn 500mg
A modified nucleoside; has been found in tRNA isolated from M. bovis; dimethylation of adjacent adenosine nucleosides is found in E. coli 16S rRNA and is important for the initiation of protein synthesis; inhibits the proliferation of L1210 leukemia cells in vitro (IC50 = 0.5 UG/ml) but does not have antitumor activity in vivo; a component of puromycin
American Research Products Inc Human platelet actiVating fact
Human platelet actiVating factor PAF ELISA Kit from CUSABIO Detection Range 4 69 ng/mL-300 ng/mL Sensitivity 1 17 ng/mL Sample serum urine cell culture supernates tissue homogenates cell lysates Method Sandwich
Cayman Chemical SynthetIc TubercIdIn 50mg
A nucleoside analog with diverse biological activities; active against S. faecalis (IC50 = 0.02 µM); cytotoxic to P388 and A549 cells (IC50s = 0.008 and 0.019 UG/ml, respectively); reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.05 µM) but is toxic to A549-ACE2 and Vero cells; increases survival in a mouse model of schistosomiasis when used at 5 mg/kg in combination with NBMPR-P but is toxic and induces mortality when administered alone at the same dose for four days
Cayman Chemical BODIPY 508CholSTRyl Ol
A fluorescently tagged cholesterol ester; ex/em = 480/508 nm, respectively; has been used to monitor cholesterol trafficking in HeLa cells
Cayman Chemical NIcotInamIde rIbosIde 5mg
A riboside form of nicotinamide; a precursor of NAD+ and a source of vitamin B3; increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1,000 μM; decreases acetylation of FOXO1 and SOD2 but not tubulin; increases NAD+ levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day; increases NAD+ in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease
ABclonal Technology Cullin 3 Rabbit pAb
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Medchemexpress LLC Thymidine-5'-monophosphate disodium salt | 33430-62-5 | 99.5% | 1 ML
Thymidine-5'-monophosphate disodium salt, also known as TMP disodium salt, is an endogenous and microbial metabolite. It is a white to off-white solid with a purity of 99.52%.
- Endogenous metabolite
- Microbial metabolite
- White to off-white solid appearance
- Purity of 99.52%
- Molecular weight of 366.17
- Chemical formula C10H13N2Na2O8P
- Soluble in water at 100 mg/mL
- Ships at room temperature (continental US)
- Recommended storage for solid form at 4°C, sealed, away from moisture and light
- Recommended storage for solution at -80°C for 6 months or -20°C for 1 month
Miltenyi Biotec, Inc. ODN 1826 Control (ODN 2138) 1mg
B-class CpG control oligodeoxyribonucleotide (murine)
Enzo Life Sciences SEEBRIGHT Green 496 dUTP (lyophilized) (50nmol)
Green 496 [5-Fluorescein] dUTP can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase. Fluorescently labeled probes can be prepared with this fluorescent nucleotide by a variety of methods including nick translation, random prime labeling, cDNA labeling and 3’-end labeling. Probes generated by these methods are suitable for use for the identification of specific sequences by in situ hybridization procedures on fixed cells and tissues by direct fluorescence detection. Green 496 dUTP can also be used for multicolor fluorescence labeling. This labeled dUTP can be used with the Nick Translation DNA Labeling System 2.0 (ENZ-GEN111). Alternative name: 5-Fluorescein dUTP. Quantity: Sufficient for approximately 98 reactions, following the recommended protocol of ENZ-GEN111. Purity: ≥93% (HPLC). Formulation: Lyophilized.