Nucleosides
Cayman Chemical ANTIBODY SGC3027 1mg
A prodrug form of the PRMT7 inhibitor SGC8158; converted by intracellular reductases to SGC8158; inhibits methylation of Hsp70 in vitro (IC50 = 2.4 µM)
Medchemexpress LLC 3-Methylcytidine | 2140-64-9 | 99.3% | 257.24 | 1 ML
3-Methylcytidine is a urinary nucleoside that can be used as a biomarker for four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer. In vitro, 3-Methylcytidine is significantly upregulated in the urine samples of breast cancer patients. It is intended for research use only.
- Can be used as a biomarker for lung cancer
- Can be used as a biomarker for gastric cancer
- Can be used as a biomarker for colon cancer
- Can be used as a biomarker for breast cancer
- Significantly upregulated in urine samples of breast cancer patients
- Intended for research use only
Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.92% | 244.20 | 25 MG
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia.
- Isomer of uridine
- Most abundant modified nucleoside in non-coding RNA
- Fine-tune and stabilize regional structures in rRNA and tRNA
- Maintain functions in mRNA decoding, ribosome assembly, processing, and translation
- Modified tRNA fragments can inhibit aberrant protein synthesis
- Hold promise for research on myelodysplastic syndrome (MDS)-related leukemia
- For research use only
Medchemexpress LLC 2′-O-Methyluridine | 2140-76-3 | 99.81% | 258.23 | 1 G
2′-O-Methyluridine is a modified nucleoside found in T. thermophile tRNA. Its serum level is decreased in breast cancer patients. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which reduces ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
- Modified nucleoside
- Found in T. thermophile tRNA
- Decreased in serum levels in breast cancer patients
- Used in siRNA targeting apolipoprotein B
- Reduces ApoB protein levels
- Prevents IFN-α production
Medchemexpress LLC 5-fluorocytidine | 2341-22-2 | MFCD00210953 | 97.0% | 261.21 g/mol | C9H12FN3O5 | 1 G
5-fluorocytidine is a fluorinated cytidine nucleoside that inhibits maturation of the 45S ribosomal RNA precursor and is provided as a characterized research reagent with storage and safety guidance from product datasheets and SDS.
- Fluorinated cytidine nucleoside.
- Inhibits maturation of the 45S ribosomal RNA precursor.
- Molecular formula C9H12FN3O5.
- Molecular weight 261.21 g/mol.
- Storage: 4°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 100.0% | 435.76 | 50 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
- Potent and orally active nucleoside antitumor agent
- Composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI)
- Inhibits thymidylate synthase (TS)
- Incorporates into DNA for antitumor activity
Selleck Chemical LLC 5-Methylcytidine
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine It is found in ribonucleic acids of animal plant and bacterial origin
Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.9% | 244.20 | 100 MG
Pseudouridine | 1445-07-4 | 99.9% | 244.20 | 100 MG
Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.92% | 244.20 | 50 MG
Pseudouridine | 1445-07-4 | 99.92% | 244.20 | 50 MG