RNAi and RNA Reagents
Invitrogen™ Silencer™ Human Phosphatase siRNA Library
Phosphatases are important regulators of biological pathways and cell signaling cascades.
Invitrogen™ Silencer™ Select Human DNA Damage Response siRNA Library
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
Invitrogen™ Silencer™ Human Tumor Suppressor siRNA Library
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.
Invitrogen™ Silencer™ Select Human Ubiquitin siRNA Library
Ubiquitination is a post-translational enzymatic modification that is essential to a wide array of cellular processes.
Invitrogen™ Silencer™ Human Membrane Trafficking siRNA Library
The Silencer™ Human Membrane Trafficking siRNA Library is designed for researchers targeting proteins known or predicted to participate in membrane trafficking or remodeling.
Invitrogen™ Silencer™ Human Drug Transporter siRNA Library
Transporter proteins play a key role in pharmacology, affecting how molecules are moved across cellular membranes.
Invitrogen™ Silencer™ Human Transcription Factor siRNA Library
Transcription factors are fast becoming promising drug targets, as they bind to and regulate the transcription of genes.
Invitrogen™ Silencer™ Select Human Epigenetics siRNA Library
The Silencer™ Select Human Epigenetics siRNA Library contains 1563 Ambion™ Silencer Select highly potent, chemically-modified siRNAs targeting 521 epigenetic enzymes, including those mediating epigenetic signaling through the acetylation and methylation of histones.
Invitrogen™ Silencer™ Human Cell Surface siRNA Library
Cell surface receptors are specialized integral membrane proteins that take part in communication between the cell and its surroundings.
Invitrogen™ Silencer™ Select Human Cell Surface siRNA Library
Cell surface receptors are specialized integral membrane proteins that take part in communication between the cell and its surroundings.
Invitrogen™ Ambion™ In Vivo Factor VII Positive Control siRNA
Ambion™ In Vivo siRNAs are designed using the proven Silencer™ Select algorithm and incorporate chemical modifications for superior serum stability with in vivo delivery.
Invitrogen™ Silencer™ Human DNA Damage Response siRNA Library
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
Invitrogen™ Silencer™ Human Ubiquitin siRNA Library
Ubiquitination is a post-translational enzymatic modification that is essential to a wide array of cellular processes.
Invitrogen™ Silencer™ Human Ion Channel siRNA Library
Ion channels are key components in a multitude of biological processes, including rapid changes in muscle cell contractions, epithelial transport of nutrients and ions, T cell activation and pancreatic beta-cell insulin release.
Invitrogen™ Silencer™ Human Nuclear Hormone Receptor siRNA Library
The nuclear hormone receptor gene family includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as receptors of unknown ligands.