Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,666
Tocris Bioscience™ Temozolomide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 85622-93-1 Molecular Formula: C6H6N6O2
| CAS | 85622-93-1 |
|---|---|
| Molecular Formula | C6H6N6O2 |
1,667
Tocris Bioscience™ SB 269970 hydrochloride
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CAS: 261901-57-9 Molecular Formula: C18H29ClN2O3S
| CAS | 261901-57-9 |
|---|---|
| Molecular Formula | C18H29ClN2O3S |
1,668
Tocris Bioscience™ BPTES
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Glutaminase Inhibitors
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 314045-39-1 |
| Purity | >95% |
| Chemical Name or Material | N,N′-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H24N6O2S3 |
| Formula Weight | 524.68 |
1,669
Tocris Bioscience™ PF 04671536 hydrochloride
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Potent and selective PDE8B/8A inhibitor
| CAS | 1305116-67-9 |
|---|---|
| Chemical Name or Material | 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C14H18N8OS.HCl |
| Formula Weight | Observed MW: 382.87 |
| Assay Percent Range | >98% |
1,670
Tocris Bioscience™ Lidocaine
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Anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.
1,671
Tocris Bioscience™ 1A-116
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Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
| CAS | 1430208-73-3 |
|---|---|
| Product Type | Inhibitor |
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H16F3N3 |
| Formula Weight | 307.31 |
1,672
Tocris Bioscience™ Panobinostat
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Pan-histone deacetylase inhibitor
| Target | Histone Deacetylase Inhibitors |
|---|---|
| CAS | 404950-80-7 |
| Purity | 0.98 |
| Chemical Name or Material | (2 E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1 H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H23N3O2 |
1,673
Tocris Bioscience™ Laropiprant
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Potent and selective prostaglandin D2 receptor antagonist
| Target | Prostanoid Receptor Antagonists |
|---|---|
| CAS | 571170-77-9 |
| Purity | 0.98 |
| Chemical Name or Material | (3 R)-4-[(4-Chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)cyclopent[b]indole-3-acetic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H19ClFNO4S |
1,674
Tocris Bioscience™ SRT 1720
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Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
| Target | Sirtuin 1/SIRT1 |
|---|---|
| CAS | 925434-55-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H23N7OS |
1,675
Tocris Bioscience™ IND 1316
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AMPK activator
| Target | AMPK Activators |
|---|---|
| CAS | 1888473-12-8 |
| Purity | 0.98 |
| Chemical Name or Material | 3-[3-(Phenylmethoxy)phenyl]-1 H-indole-2-carboxylic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H17NO3 |
1,676
Tocris Bioscience™ NIR Dye s775z, NHS
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Bright and photostable non-aggregating near-IR cyanine dye. Reactive group: NHS ester
1,677
Tocris Bioscience™ ERB 041
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CAS: 524684-52-4 Molecular Formula: C15H10FNO3
| CAS | 524684-52-4 |
|---|---|
| Molecular Formula | C15H10FNO3 |
1,678
Tocris Bioscience™ Methysergide maleate
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CAS: 129-49-7 Molecular Formula: C25H31N3O6
| CAS | 129-49-7 |
|---|---|
| Molecular Formula | C25H31N3O6 |
1,679
Tocris Bioscience™ Methylmalonate
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Succinate dehydrogenase inhibitor
1,680
Tocris Bioscience™ ICA 121431
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CAS: 313254-51-2 Molecular Formula: C23H19N3O3S2
| CAS | 313254-51-2 |
|---|---|
| Molecular Formula | C23H19N3O3S2 |