Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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2,956
Tocris Bioscience™ AMG 517
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CAS: 659730-32-2 Molecular Formula: C20H13F3N4O2S
| CAS | 659730-32-2 |
|---|---|
| Molecular Formula | C20H13F3N4O2S |
2,957
Tocris Bioscience™ AZD 9291
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Potent mutant-selective EGFR inhibitor
| Purity | 98% |
|---|---|
| Recommended Storage | Store at -20°C |
2,958
Tocris Bioscience™ Docetaxel
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CAS: 114977-28-5 Molecular Formula: C43H53NO14
| CAS | 114977-28-5 |
|---|---|
| Molecular Formula | C43H53NO14 |
2,959
Tocris Bioscience™ (+)-Igmesine hydrochloride
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Selective sigma1 ligand; antidepressant
| CAS | 130152-35-1 |
|---|---|
| Solubility | Soluble to 50mM in DMSO |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H29N.HCl |
| Formula Weight | Observed MW: 355.94 |
| Assay Percent Range | >98% |
2,960
Tocris Bioscience™ GNF 7
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Ras signaling inhibitor; inhibits Ack1 and GCK
| Target | Small G Protein Inhibitors |
|---|---|
| CAS | 839706-07-9 |
| Purity | >98% |
| Chemical Name or Material | Ras GTPase Inhibitors |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H24F3N7O2 |
| Formula Weight | 547.53 |
2,961
Tocris Bioscience™ AR-C 141990 hydrochloride
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MCT1 inhibitor
2,962
Tocris Bioscience™ CHC
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MCT inhibitor; decreases glycoloysis
2,963
Tocris Bioscience™ RIPGBM
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RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
| Target | RIP Kinase Inhibitors |
|---|---|
| CAS | 355406-76-7 |
| Purity | 98% |
| Chemical Name or Material | N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H21FN2O3 |
2,964
Tocris Bioscience™ ANA 12
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CAS: 219766-25-3 Molecular Formula: C22H21N3O3S
| CAS | 219766-25-3 |
|---|---|
| Molecular Formula | C22H21N3O3S |
2,965
Tocris Bioscience™ Calhex 231 hydrochloride
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CAS: 652973-93-8 Molecular Formula: C25H27ClN2O
| CAS | 652973-93-8 |
|---|---|
| Molecular Formula | C25H27ClN2O |
2,966
Tocris Bioscience™ TP 238
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CECR2 and BPTF/FALZ inhibitor
2,967
Tocris Bioscience™ AF-DX 116
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CAS: 102394-31-0 Molecular Formula: C24H31N5O2
| CAS | 102394-31-0 |
|---|---|
| Molecular Formula | C24H31N5O2 |
2,968
Tocris Bioscience™ UCB 35625
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CAS: 202796-42-7 Molecular Formula: C30H37Cl2IN2O2
| CAS | 202796-42-7 |
|---|---|
| Molecular Formula | C30H37Cl2IN2O2 |
2,969
Tocris Bioscience™ ICA 069673
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KV7.2/KV7.3 channel opener
| CAS | 582323-16-8 |
|---|---|
| Chemical Name or Material | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C11H6ClF2N3O |
| Formula Weight | Observed MW: 269.63 |
| Assay Percent Range | >99% |
2,970
Tocris Bioscience™ Remdesivir
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Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucelotide prodrug
| Target | RNA/DNA Polymerase Inhibitors |
|---|---|
| CAS | 1809249-37-3 |
| Purity | 0.98 |
| Chemical Name or Material | 2-Ethylbutyl (2 S)-2-[[-[[(2 R,3 S,4 R,5 R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H35N6O8P |