Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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406
Tocris Bioscience™ Oxcarbazepine
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CAS: 28721-07-5 Molecular Formula: C15H12N2O2
| CAS | 28721-07-5 |
|---|---|
| Molecular Formula | C15H12N2O2 |
407
Tocris Bioscience™ SMIP 004
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SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
| Target | Ubiquitin Ligase (E3) Inhibitors |
|---|---|
| CAS | 143360-00-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-(4-Butyl-2-methylphenyl)acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H19NO |
408
Tocris Bioscience™ BromoTag™ cis-AGB1
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Negative control for BromoTag AGB1 (Cat.No. 7686)
409
Tocris Bioscience™ BMS 265246, >97%
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CAS: 582315-72-8 Molecular Formula: C18H17F2N3O2
| CAS | 582315-72-8 |
|---|---|
| Molecular Formula | C18H17F2N3O2 |
410
Tocris Bioscience™ RP 67580
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CAS: 135911-02-3 Molecular Formula: C29H30N2O2
| CAS | 135911-02-3 |
|---|---|
| Molecular Formula | C29H30N2O2 |
411
Tocris Bioscience™ VH 032 amide-PEG4-acid
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VHL ligand with PEG linker and terminal acid for onward chemistry
412
Tocris Bioscience™ UoS 12258
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Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro)
| CAS | 875927-64-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H19FN2O2S |
| Formula Weight | 334.41 |
413
Tocris Bioscience™ TFM-4AS-1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 188589-61-9 Molecular Formula: C27H33F3N2O2
| CAS | 188589-61-9 |
|---|---|
| Molecular Formula | C27H33F3N2O2 |
414
Tocris Bioscience™ FMF-04-159-2
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Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
415
Tocris Bioscience™ CATPB
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416
Tocris Bioscience™ MRS 2365
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Highly potent and selective P2Y1 agonist
417
Tocris Bioscience™ RWJ 67657
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CAS: 215303-72-3 Molecular Formula: C27H24FN3O
| CAS | 215303-72-3 |
|---|---|
| Molecular Formula | C27H24FN3O |
418
Tocris Bioscience™ MLS 1547
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G protein-biased D2 partial agonist
| CAS | 315698-36-3 |
|---|---|
| Chemical Name or Material | 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H19ClN4O |
| Formula Weight | Observed MW: 354.83 |
| Assay Percent Range | >98% |
419
Tocris Bioscience™ GSK 1016790A
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Potent TRPV4 agonist
| Product Type | Agonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H32Cl2N4O6S2 |
| Formula Weight | 655.61 |
420
Tocris Bioscience™ MDL 100907
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CAS: 139290-65-6 Molecular Formula: C22H28FNO3
| CAS | 139290-65-6 |
|---|---|
| Molecular Formula | C22H28FNO3 |