Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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466
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480
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467
Tocris Bioscience™ DCEBIO
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Activates Cl- conductance and hKCa3.1 channels
| CAS | 60563-36-2 |
|---|---|
| Solubility | Soluble to 100mM in DMSO |
| Chemical Name or Material | 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C9H8Cl2N2O |
| Formula Weight | Observed MW: 231.08 |
| Assay Percent Range | >99% |
468
Tocris Bioscience™ 4-Chlorophenylguanidine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Urokinase inhibitor
469
Tocris Bioscience™ A 410099.1 amide-PEG3-amine
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IAP ligand with PEG linker and terminal amine for onward chemistry
470
Tocris Bioscience™ CI 988
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CAS: 130332-27-3 Molecular Formula: C35H42N4O6
| CAS | 130332-27-3 |
|---|---|
| Molecular Formula | C35H42N4O6 |
471
Tocris Bioscience™ Mirtazapine
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CAS: 85650-52-8 Molecular Formula: C17H19N3
| CAS | 85650-52-8 |
|---|---|
| Molecular Formula | C17H19N3 |
472
Tocris Bioscience™ Thalidomide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Binds cereblon; also TNF-α synthesis inhibitor
473
Tocris Bioscience™ MSC 1186
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Potent and selective SRPK family inhibitor
| Target | SRPK3/STK23 |
|---|---|
| CAS | 2871698-23-4 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-[[[2-(6-Chloro-7-fluoro-1H-benzimidazol-2-yl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17ClFN7O2S |
474
Tocris Bioscience™ BGP 15
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PARP inhibitor; cytoprotectant
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H22N4O2.2HCl |
| Formula Weight | 351.27 |
475
Tocris Bioscience™ FTBMT
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Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
| CAS | 1358575-02-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H16F4N4O |
| Formula Weight | 392.35 |
476
Tocris Bioscience™ SF 11
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CAS: 443292-81-7 Molecular Formula: C27H30N2O2S
| CAS | 443292-81-7 |
|---|---|
| Molecular Formula | C27H30N2O2S |
477
Tocris Bioscience™ Zonisamide
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CAS: 68291-97-4 Molecular Formula: C8H8N2O3S
| CAS | 68291-97-4 |
|---|---|
| Molecular Formula | C8H8N2O3S |
478
Tocris Bioscience™ DMCM hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1215833-62-7 Molecular Formula: C17H19ClN2O4
| CAS | 1215833-62-7 |
|---|---|
| Molecular Formula | C17H19ClN2O4 |
479
Tocris Bioscience™ YM 244769
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1780390-65-9 Molecular Formula: C26H23ClFN3O3
| CAS | 1780390-65-9 |
|---|---|
| Molecular Formula | C26H23ClFN3O3 |
480
Tocris Bioscience™ RS 102221 hydrochloride
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CAS: 187397-18-8 Molecular Formula: C27H32ClF3N4O7S
| CAS | 187397-18-8 |
|---|---|
| Molecular Formula | C27H32ClF3N4O7S |