Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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466
Tocris Bioscience™ Ortho AP 1867
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective binding ligand for FKBP12F36V; precursor for dTAG compounds
| Target | FKBP12 |
|---|---|
| CAS | 2230613-03-1 |
| Purity | 0.98 |
| Chemical Name or Material | 2-(2-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C38H47NO11 |
467
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Thermo Scientific Chemicals Afatinib
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Thermo Scientific Chemicals Afatinib
CAS: 850140-72-6 Molecular Formula: C24H25ClFN5O3
| CAS | 850140-72-6 |
|---|---|
| Molecular Formula | C24H25ClFN5O3 |
468
R&D Systems™ Cy5-Fuc Labeled S2[3]f (Cy5-S2[3]f)
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Used as a ligand for lectins and to study glycan protein interaction
469
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Amentoflavone, Thermo Scientific™
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Amentoflavone, Thermo Scientific™
CAS: 1617-53-4 Molecular Formula: C30 H18 O10 Molecular Weight (g/mol): 538.46 InChI Key: YUSWMAULDXZHPY-UHFFFAOYSA-N IUPAC Name: 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one SMILES: OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C(=C2O1)C1=CC(=CC=C1O)C1=CC(=O)C2=C(O)C=C(O)C=C2O1
| CAS | 1617-53-4 |
|---|---|
| Molecular Weight (g/mol) | 538.46 |
| SMILES | OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C(=C2O1)C1=CC(=CC=C1O)C1=CC(=O)C2=C(O)C=C(O)C=C2O1 |
| IUPAC Name | 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| InChI Key | YUSWMAULDXZHPY-UHFFFAOYSA-N |
| Molecular Formula | C30 H18 O10 |
470
Tocris Bioscience™ BAY 593
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Geranylgeranyltransferase-I (GGTase-I) inhibitor
471
Tocris Bioscience™ MPD 2
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SARS-CoV-2 Mpro Degrader (PROTAC™)
472
| Shipping Condition | No special requirements |
|---|---|
| CAS | 58-46-8 |
| Color | White to Light-yellow to Beige |
| Purity | ≥97.5% |
| Physical Form | Crystalline Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Tetrabenazine |
| Recommended Storage | Refrigerator +4°C |
| Molecular Formula | C19 H27 N O3 |
| EINECS Number | 200-383-6 |
| Melting Point | 124°C to 130°C |
| Product Line | Life science |
473
Tocris Bioscience™ Janelia Fluor™ 646b, NHS ester
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Blinking fluorescent dye (Reactive group: NHS ester). Application: super resolution microscopy (SRM) including SMLM
474
Tocris Bioscience™ BL660-NO
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Nitric oxide activity-based sensing NIR bioluminescent probe
475
Tocris Bioscience™ SIM1
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Potent and selective trivalent BET Bromodomain Degrader (PROTAC™)
476
Tocris Bioscience™ PF 06651600 malonate
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Potent and selective JAK3 inhibitor
| CAS | 2140301-97-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H19N5O.C3H4O4 |
477
Tocris Bioscience™ EPZ 015666
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Potent and selective PRMT5 inhibitor
| CAS | 1616391-65-1 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H25N5O3 |
| Formula Weight | 383.44 |
478
Tocris Bioscience™ CY 09
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Inflammasomes Inhibitors
| CAS | 1073612-91-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H12F3NO3S2 |
479
Tocris Bioscience™ Autophinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent VPS34 inhibitor
480
Tocris Bioscience™ CX08005
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Competitive PTP1B inhibitor
| CAS | 1256341-22-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H39N04 |