Bioactive Small Molecules
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Filtered Search Results
MYBIOSOURCE ANTI-MAP3K8 RABBIT TPL2 0.1ML
NC3346748 ANTI-MAP3K8 RABBIT TPL2 0.1ML
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CAMBRIDGE ISOTOPE LABORATORIES PCDD/PCDF WINDOW DEFINING ISOM
NC2327041 PCDD/PCDF WINDOW DEFINING ISOM
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SELLECK CHEMICAL LLC HARRINGTONINE 5MG
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NC2606146 HARRINGTONINE 5MG
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ZYAGEN LABS MOUSE CD1 EMBRYO SAG PARA
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502930435 MOUSE CD1 EMBRYO SAG PARA
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Medchemexpress LLC Betaine-13C3 | 309762-22-9 | 99.9% | 1 MG
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Betaine-13C3 (Trimethylglycine-13C3) is the 13C labeled isotope of Betaine. This natural compound is found ubiquitously in plants, animals, and microorganisms, and is an active methyl-donor that maintains normal DNA methylation patterns. It also acts as an osmolyte, helping to maintain cellular water and ion balance, particularly in heat-stressed birds, and may promote intestinal microbial fermentation activity.
- Functions as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Maintains normal DNA methylation patterns.
- Acts as an osmolyte to maintain cellular water and ion balance.
- Improves avian capacity against heat stress.
- Promotes various intestinal microbes against osmotic variations.
- Improves microbial fermentation activity.
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TARGETMOL CHEMICALS INC YHO-13351 FREE BASE 10MG
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Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YHO-13351 free base is the water-soluble prodrug of YHO-13177 which is an inhibitor of BCRP . purity: 100%
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Medchemexpress LLC Bisindolylmaleimide I | 133052-90-1 | 98.2% | 412.48 | 50 MG
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Bisindolylmaleimide I is a cell-permeable and reversible protein kinase C (PKC) inhibitor, identified with IC50 values for various PKC isoforms. It also acts as a glycogen synthase kinase-3 (GSK-3) inhibitor and is for research use only.
- Cell-permeable and reversible PKC inhibitor (IC50 for PKCα, PKCβI, PKCβII, PKCγ: 16-20 nM)
- GSK-3 inhibitor
- Inhibits human platelet aggregation
- Protects against *Bacillus anthracis* lethal toxin-mediated cytotoxicity
- Inhibits α-thrombin-induced P47 phosphorylation
- Reduces GSK-3 activity in adipocyte lysates
- Inhibits exosome and microvesicle release from PC3 cells
- Enhances cytotoxicity of 5-fluorouracil
- Demonstrates *in vivo* activity in mice and shrews
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Medchemexpress LLC Ceftibuten dihydrate | 118081-34-8 | 99.2% | 50 MG
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Ceftibuten dihydrate is an orally active cephalosporin antibiotic with potent in vitro activity against a wide range of gram-negative and certain gram-positive pathogens. It is stable in the presence of most β-lactamase-producing organisms, with the exception of Bacteroides fragilis.
- Orally active cephalosporin antibiotic
- Potent in vitro activity against a broad spectrum of gram-negative and some gram-positive pathogens
- Highly active against Haemophilus influenza, Escherichia coli, Klebsiella sp., and Proteus sp.
- Moderately active against Serratia sp. and Streptococcus pyogenes
- Very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains = 0.25 μg/ml)
- Stable in the presence of most β-lactamase-producing organisms, except Bacteroides fragilis
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Cayman Chemical ANTIBODY EHT 1864 5mg
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An inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively; has inhibitory effects on APP processing, breast cancer cell invasion, and growth of dendritic spines
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Medchemexpress LLC BGSN3 (Benzyl-Guanine Substrate) | 2996069-91-9 | 98.1% | 381.39 | 10 MM * 1 ML
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BGSN3 is a click chemistry reagent containing an Azide group, making it suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. It is also an effective substrate for SNAP-tag and H5 enzymes, with IC50 values of 17.8 μM and 10 μM respectively, and can be used for direct immobilization of these tags on solid surfaces.
- Good substrate for SNAP-tag and H5 enzymes
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Effective for protein/enzyme labeling using SNAP-tag technology
- Suitable for direct immobilization on solid surfaces
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Cayman Chemical ANTIBODY AZD 0095 5mg
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An MCT4 inhibitor (IC50 = 1.3 nM); selectively inhibits lactate influx in NCI H358 cells (IC50 = 6.1 nM), which highly express MCT4 and do not express MCT1, over lactate influx in K562 cells (IC50 = >30 µM), which highly express MCT1 and do not express MCT4; inhibits the proliferation of NCI H358 cells (IC50 = 26 nM); reduces tumor growth in an NCI H358 mouse xenograft model at 100 mg/kg twice per day in combination with cediranib
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BIOIVT LLC MG HUMAN XTREME 200D S9
502462845 MG HUMAN XTREME 200D S9
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TARGETMOL CHEMICALS INC MRT68921 25MG
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502693759 MRT68921 25MG
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VITALQUAN LLC ZIGIR
NC2055548 ZIGIR
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SELLECK CHEMICAL LLC TUCATINIB IRBINITINIB ONT-380
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NC1973601 TUCATINIB IRBINITINIB ONT-380
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