Protein Modification Reagents
Sigma Aldrich Fine Chemicals Biosciences Pepsin Agarose from porcin
Pepsin is an enzyme found in gastric secretion.
Cayman Chemical AzIdo-dPEG7-amIn 10mg
A heterobifunctional PEGylated linker; contains a reactive NH2 end group, as well as an azide functional group for use in click chemistry reactions; has been used as a linker in the synthesis of bivalent mTOR inhibitors
eMolecules N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 2107272-96-6 | | 10mg
Broadpharm | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 10mg | 298819349 | BP-23008 | 97.000 | 2107272-96-6 | | 870.450 | C44H63ClF3N3O9
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Medchemexpress LLC Dspe-thiol | 144735-82-0 | MFCD29079392 | 90.0% | 836.19 g/mol | C44H86NO9PS | 1 MG
DSPE-Thiol is a thiol-capped distearoylphosphatidylethanolamine used to introduce reactive sulfhydryl groups into lipid assemblies. The thiol headgroup enables selective covalent coupling via thiol-maleimide chemistry and can be used to create functionalized liposomes or phospholipid dimers.
- Thiol headgroup enables selective reaction with maleimide reagents.
- Facilitates preparation of phospholipid dimers and lipid conjugates.
- Useful for liposome functionalization and surface modification.
- Supplied as a research-grade phospholipid with documented purity and molecular data.
Medchemexpress LLC DSPE-PEG-maleimide (MW 3400) ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC52H93N3NaO13P | 50 MG
DSPE-PEG-maleimide (MW 3400) ammonium is a phospholipid-polyethylene glycol conjugate bearing a terminal maleimide reactive group. Supplied as the ammonium salt with a nominal PEG molecular weight of 3,400 Da, it is used to introduce thiol-reactive functionality into lipid assemblies for site-specific conjugation and formulation of PEGylated lipid nanoparticles and nanostructured lipid carriers.
- Provides maleimide functionality for thiol-specific conjugation.
- Anchors into lipid bilayers via DSPE for stable incorporation into liposomes and nanoparticles.
- PEG chain (3,400 Da) imparts steric stabilization and extended circulation.
- Compatible with thiol-containing ligands for targeted conjugation.
- Typically supplied at ≥95% purity; store under dry and low-temperature conditions.
Medchemexpress LLC t-Boc-N-amido-PEG5-acetic acid | 890152-41-7 | MFCD31656900 | 98.0% | 395.45 | C17H33NO9 | 1 G
t-Boc-N-amido-PEG5-acetic acid is a Boc-protected PEG-based linker used for assembling PROTACs and other bioconjugates. It provides a flexible, hydrophilic spacer with a terminal acetic acid and a Boc-protected amine, enabling standard coupling and selective deprotection steps during synthesis.
- Provides a five-unit polyethylene glycol spacer for flexible linkage.
- Contains a terminal acetic acid for straightforward conjugation chemistry.
- Features a Boc-protected amine to allow selective deprotection and functionalization.
- Suitable for synthesis of heterobifunctional degraders and bioconjugates.
- Available in multiple pack sizes for research-scale synthesis.
eMolecules Fmoc-PEG3-NHS ester | 1352827-47-4 | MFCD28142471 | 1g
Broadpharm | Fmoc-PEG3-NHS ester | 1g | 263744723 | BP-22334 | 98.000 | 1352827-47-4 | MFCD28142471 | 540.569 | C28H32N2O9
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STA PHARMACEUTICAL US LLC Fmoc-NH-PEG4-CH2COOH | 5 g | CAS 437655-95-3 | MDL MFCD26142981
Fmoc-NH-PEG4-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-95-3
- MDL: MFCD26142981
- InChIKey: XPNLDOFYRFOXLR-UHFFFAOYSA-N
- Molecular Weight: 473.522
- Molecular Formula: C25H31NO8
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid
- SMILES: O=C(COCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Cayman Chemical Boc-NH-PEG3-CH2CoH 250mg
A building block; has been used as a linker in the synthesis of PROTACs targeting MEK; has been used as a spacer in the synthesis of radiolabeled probes for dual labeling of tumor integrin αVβ3 and GRPR in tumor tissue in vivo
Medchemexpress LLC Hydroxy-PEG4-(CH2)2-Boc | 518044-32-1 | MFCD11041117 | 99.3% | 322.39 g/mol | C15H30O7 | 100 G
Hydroxy-PEG4-(CH2)2-Boc is a PEG4-based linker with a terminal hydroxyl and a tert-butyl (Boc) protected group, supplied for use in synthetic and medicinal chemistry applications such as antibody-drug conjugate (ADC) and PROTAC assembly. It is a non-cleavable spacer with a molecular weight of 322.39 g/mol and a chemical formula of C15H30O7.
- PEG4 spacer with terminal hydroxyl
- Boc-protected tert-butyl ester functional group
- Non-cleavable linker for ADC and PROTAC assembly
- Approximately 99.3% purity suitable for medicinal chemistry
- Available in laboratory-scale pack sizes, including 100 G
- Recommended storage: -20°C for long-term stability; follow solvent-specific conditions
![Medchemexpress LLC Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 1263166-93-3 | MFCD19705418 | 97.0% | 324.42 g/mol | C17H28N2O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000208868.png-250.jpg)
Medchemexpress LLC Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 1263166-93-3 | MFCD19705418 | 97.0% | 324.42 g/mol | C17H28N2O4 | 25 MG
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker containing a strained bicyclo[6.1.0]nonyne (BCN) alkyne and a terminal amine. It enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation and is commonly used in PROTAC assembly and linker installation.
- Contains BCN strained alkyne for SPAAC click chemistry.
- Peg2 spacer with a terminal primary amine.
- Purity: 97.0% (HPLC).
- Physical form: colorless to light yellow oil.
- Molecular weight: 324.42 g/mol; formula C17H28N2O4.
- Storage: protect from light; in solvent store at -80°C (6 months) or -20°C (1 month).