Protein Modification Reagents
Medchemexpress LLC Mal-amido-PEG2-TFP ester | 1431291-44-9 | 98.7% | 250 MG
Mal-amido-PEG2-TFP ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This product is for research use only.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs exploit the intracellular ubiquitin-proteasome system
- PROTACs selectively degrade target proteins
Medchemexpress LLC TOS-PEG2-O-PROPARGYL - 100MG
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458).Purity: 98.47%.CAS No. : 1119249-30-7
![eMolecules 1262681-31-1 | BIOTIN-PEG4-ALKYNE | AstaTech | MFCD22380755 | 457.590 | C21H35N3O6S | 95.000 | O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCOCCOCCOCCOCC#C | 0.1g | 533785764](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000483692.jpg-250.jpg)
eMolecules 1262681-31-1 | BIOTIN-PEG4-ALKYNE | AstaTech | MFCD22380755 | 457.590 | C21H35N3O6S | 95.000 | O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCOCCOCCOCCOCC#C | 0.1g | 533785764
BIOTIN-PEG4-ALKYNE | AstaTech | 1262681-31-1 | MFCD22380755 | 457.590 | C21H35N3O6S | 95.000 | O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCOCCOCCOCCOCC#C | 0.1g | 533785764
Medchemexpress LLC DBCO-PEG4-C2-acid | 1537170-85-6 | 99.2% | 25 MG
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. This product appears as a white to yellow solid.
- PEG-based PROTAC linker
- Used in PROTACs synthesis
- Click chemistry reagent
- Contains a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Appearance: White to yellow solid
- Molecular Weight: 552.62
- Formula: C30H36N2O8
eMolecules 1807534-77-5 | Fluorescein-PEG3-(N-Boc)-Amine | Broadpharm | MFCD28505583 | 681.760 | C34H39N3O10S | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12 | 250mg | 550803911
Fluorescein-PEG3-(N-Boc)-Amine | Broadpharm | 1807534-77-5 | MFCD28505583 | 681.760 | C34H39N3O10S | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12 | 250mg | 550803911
Medchemexpress LLC m-PEG-DMG | 5,000 Da (average) | 10 MG
m-PEG-DMG (MW 5000) is a methoxy-terminated polyethylene glycol (PEG) conjugated to a dimyristoyl glycerol (DMG) lipid tail used as a PEG-lipid component in lipid nanoparticle and drug delivery formulations. It provides steric stabilization and can improve the delivery efficiency and tissue specificity of poorly soluble drugs.
- Used as a PEG-lipid in lipid nanoparticles and drug delivery research.
- Average molecular weight about 5,000 Da.
- Typically supplied as a powder with recommended storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Solubility in DMSO approximately 50 mg/mL (ultrasonic assistance may be required).
- Provides steric stabilization to nanoparticle surfaces and can reduce aggregation and opsonization.
![Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | MFCD28505520 | 99.3% | 417.48 g/mol | C17H27N3O7S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203782.png-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | MFCD28505520 | 99.3% | 417.48 g/mol | C17H27N3O7S | 100 MG
Azide-PEG5-Tos is a tosyl-activated azido polyethylene glycol linker (PEG5) used as a cleavable spacer and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It contains an azide functional group for copper-catalyzed and strain-promoted azide-alkyne cycloaddition, and a tosyl leaving group for nucleophilic substitution. Supplied for research use with high purity and good DMSO solubility.
- Cleavable 5-unit PEG linker suitable for ADC and bioconjugation chemistry.
- Azide functional group enables CuAAC and SPAAC click reactions.
- Tosyl-activated for nucleophilic substitution and conjugation.
- High purity (≈99.3%).
- Soluble in DMSO at ≥100 mg/mL for convenient stock solutions.
Cayman Chemical dPE-PEG 2000-NHS 100mg
A PEGylated derivative of DSPE; has been used in the generation of micelles and in combination with other lipids in the formation of liposomes; intravenous injection of liposomes containing DSPE-PEG(2000)-NHS ester localize to mouse liver and tumor tissue; liposomes containing DSPE-PEG(2000)-NHS ester conjugated to H6 peptide and encapsulating doxorubicin reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model
Cayman Chemical BIOnT PROTAC Fragmnt lbrar 5mg
Customers are supplied with the following data package for EAch fragment purchases: • Aqueous buffer 1H NMR raw data file • Structures and physiochemical properties in an sd file • SPR Clean Screen results The parameters used in the design of the library are: • Heavy atoms ≤ 16 • clogP ≤ 3 • Hydrogen bond donors ≤ 1 • Hydrogen bond acceptors ≤ 3 • tPSA ≤ 60 • Rotatable bonds ≤ 3
Medchemexpress LLC APN-C3-PEG4-azide | 2183440-32-4 | 97.97% | C24H32N6O6 | 50 MG
APN-C3-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Bioworld D(+) Galactose, 250 g
An monosaccharidic aldo hexose potentially useful in aging studies. Specifications:High Purity GradeSpecific Rotation (2% water): 79 - 81°Appearance: White PowderBoiling Point : 410.8 °CDensity : 1.5 g/cm3HS Code : 29400090Melting Point: 168-170 °CRTECS Number: LW5490000
Medchemexpress LLC Biotin-PEG6-silane | 00-00-0 | 98.0% | 783.06 g/mol | C34H66N4O12SSi | 5 MG
Biotin-PEG6-silane is a biotinylated PEG6 linker bearing a terminal silane group, intended for use in chemical biology applications such as PROTAC assembly, affinity capture, and surface functionalization. The PEG6 spacer positions the biotin tag while the silane enables surface coupling to silica and glass substrates, supporting conjugation and immobilization workflows.
- Provides a biotin tag with a six-unit PEG spacer.
- Terminal silane enables covalent attachment to silica and glass surfaces.
- Suitable for PROTAC linker assembly and affinity capture workflows.
- PEG spacer improves solubility and reduces steric hindrance.
- High purity for reproducible experimental results.
Medchemexpress LLC Endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | 325.40 | 100 MG
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs degrade target proteins using the intracellular ubiquitin-proteasome system.
- Purity: 98.0%
- Molecular weight: 325.40
- Formula: C17H27NO5
- Appearance: Oil
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)