Protein Modification Reagents
![eMolecules 1821017-46-2 | Methyltetrazine-Sulfo-NHS ester | Broadpharm | MFCD29052195 | 429.340 | C15H12N5NaO7S | 95.000 | [Na+].Cc1nnc(nn1)-c1ccc(CC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)cc1 | 10mg | 296213298](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464935.JPG-250.jpg)
eMolecules 1821017-46-2 | Methyltetrazine-Sulfo-NHS ester | Broadpharm | MFCD29052195 | 429.340 | C15H12N5NaO7S | 95.000 | [Na+].Cc1nnc(nn1)-c1ccc(CC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)cc1 | 10mg | 296213298
Methyltetrazine-Sulfo-NHS ester | Broadpharm | 1821017-46-2 | MFCD29052195 | 429.340 | C15H12N5NaO7S | 95.000 | [Na+].Cc1nnc(nn1)-c1ccc(CC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)cc1 | 10mg | 296213298
Medchemexpress LLC Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide | 2599839-59-3 | 95.0% | C47H67N9O10SSi | 25 MG
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. It functions as an enrichment handle for cell surface glycoproteins, facilitating protein labeling.
- Clickable, acid-cleavable biotin-picolyl azide
- Functions as an enrichment handle for cell surface glycoproteins
- Suitable for protein labeling
- Azide group enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC)
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202398.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG
(2-pyridyldithio)-PEG4 acid is a cleavable PEG linker containing four ethylene glycol units and a 2-pyridyldithio terminal group, used to attach payloads to antibodies via disulfide chemistry for antibody-drug conjugate (ADC) synthesis and other bioconjugation applications.
- Cleavable disulfide-based linker for controlled payload release.
- Four-unit PEG spacer provides flexibility and solubility.
- 2-pyridyldithio group enables facile thiol-based conjugation.
- Suitable for ADC synthesis and general bioconjugation workflows.
- Supplied as a solid and commonly available in a 100 mg pack size.
eMolecules 581065-94-3 | Tos-PEG5 t-butyl ester | Broadpharm | MFCD22574810 | 476.580 | C22H36O9S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 250mg | 353441935
Tos-PEG5 t-butyl ester | Broadpharm | 581065-94-3 | MFCD22574810 | 476.580 | C22H36O9S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 250mg | 353441935
eMolecules 928292-69-7 | Amino-PEG10-amine | Broadpharm | MFCD28122962 | 500.630 | C22H48N2O10 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 254745494
Amino-PEG10-amine | Broadpharm | 928292-69-7 | MFCD28122962 | 500.630 | C22H48N2O10 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 254745494
Broadpharm TCO-PEG4-NHS ester, 1613439-69-2, MFCD28118912, 25mg
Formula: C24H38N2O10, Purity: 95%, MW: 514.6, TCO-PEG4-NHS Ester is a PEG derivative containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water-solubility and a decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety.
(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCC\C=C/CCCCCCCC | 25mg | 718091950](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502471462.JPG-250.jpg)
eMolecules 474922-90-2 | 18:1 PEG PE, MW 5,000 | Broadpharm846.137 | C45H84NO11P | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCC\C=C/CCCCCCCC | 25mg | 718091950
18:1 PEG PE, MW 5,000 | Broadpharm | 474922-90-2846.137 | C45H84NO11P | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCC\C=C/CCCCCCCC | 25mg | 718091950
Medchemexpress LLC Methyltetrazine-PEG5-alkyne | 1802907-97-6 | 98.0% | C20H26N4O5 | 250 MG
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It is provided as a pink to red solid with a purity of 98.0% for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Purity of 98.0%
- Appearance: pink to red solid
- Store at 4°C, under nitrogen
- Soluble in DMSO
Medchemexpress LLC Dbco-PEG4-acetic-val-cit-pab | 96.7% | 855.97 | C45H57N7O10 | 25 MG
DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable four-unit PEG linker containing a dibenzocyclooctyne (DBCO) group and a Val-Cit-PAB cleavable spacer, designed for use in antibody-drug conjugate synthesis and click-chemistry conjugation.
- Contains DBCO for strain-promoted alkyne-azide cycloaddition (SPAAC).
- Val-Cit-PAB spacer is enzymatically cleavable for intracellular payload release.
- Designed for assembly of antibody-drug conjugates and payload conjugation.
- Available in small pack sizes suitable for research applications.
- Powder stable at -20°C for long-term storage; solution stability is temperature dependent.
Medchemexpress LLC Apn-c3-peg4-azide | 2183440-32-4 | 97.97% | C24H32N6O6 | 100 MG
APN-C3-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in PROTAC synthesis for selective degradation of target proteins.
Medchemexpress LLC 3,6,9-trioxa-12-azaheptadecan-17-oic acid, 1-amino-16-[[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)m | 710323-40-3 | 99.7% | 615.64 | C27H37N9O8 | 5 MG
Folate-PEG3-amine is a cleavable three-unit polyethylene glycol (PEG) linker bearing a terminal primary amine and a folate-targeting moiety. It is designed for use as a spacer in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates, facilitating folate receptor-mediated targeting in research applications.
- Cleavable three-unit PEG spacer to separate payload and targeting ligand.
- Terminal primary amine for straightforward conjugation chemistries, such as NHS esters and activated carboxyls.
- High purity suitable for research (LCMS reported 99.69%).
- Water-soluble and compatible with common bioconjugation workflows.
- Supplied in small research quantities for experimental use.
Medchemexpress LLC 6-FAM-PEG3-azide | 412319-45-0 | 98.1% | C29H28N4O9 | 10MG
6-FAM-PEG3-Azide is a fluorescent labeling reagent composed of a 6-carboxyfluorescein (6-FAM) dye linked to an azide via a PEG3 spacer. It is designed for covalent conjugation to alkyne-functionalized partners using copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC), enabling fluorescent labeling of oligonucleotides and other biomolecules.
- Fluorescent labeling with excitation 498 nm and emission 532 nm.
- PEG3 spacer improves water solubility and reduces steric hindrance.
- Azide functional group for CuAAC and SPAAC click chemistry.
- Solid, light yellow to yellow form stable when stored as powder at -20°C.
- High purity (~98.1%) suitable for analytical and labeling applications.