Protein Modification Reagents
Medchemexpress LLC Biotin-PEG4-alcohol | 1217609-84-1 | 98.0% | C18H33N3O6S | 10MG
Biotin-PEG4-OH is a biotinylated polyethylene glycol linker with a terminal hydroxyl group, designed for use as a flexible spacer and affinity tag in chemical biology and PROTAC synthesis. The PEG4 spacer increases solubility and reduces steric hindrance while enabling conjugation to biomolecules and small-molecule ligands.
Medchemexpress LLC PC DBCO-PEG4-NHS ester | 2055025-02-8 | MFCD30458047 | 96.9% | 945.96 | C47H55N5O16 | 5 MG
PC DBCO-PEG4-NHS ester is a PEG-based click chemistry linker reagent designed for bioconjugation and surface modification. The molecule combines a dibenzocyclooctyne (DBCO) moiety for copper-free click reactions with an NHS ester that reacts readily with primary amines, enabling efficient attachment to peptides, proteins, and other biomolecules.
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC).
- NHS ester reacts with primary amines to form stable amide bonds.
- PEG4 spacer improves solubility and reduces steric hindrance.
- High purity suitable for research use and sensitive conjugation workflows.
- Stable when stored cold and protected from moisture to maintain reactivity.
eMolecules 2141981-87-3 | TCO-PEG2-amine | Broadpharm300.399 | C15H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC1CCC\C=C\CC1 | 100mg | 433947015
TCO-PEG2-amine | Broadpharm | 2141981-87-3300.399 | C15H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC1CCC\C=C\CC1 | 100mg | 433947015
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG4-CH2COOH | 50 g | CAS 437655-95-3 | MDL MFCD26142981
Fmoc-NH-PEG4-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-95-3
- MDL: MFCD26142981
- InChIKey: XPNLDOFYRFOXLR-UHFFFAOYSA-N
- Molecular Weight: 473.522
- Molecular Formula: C25H31NO8
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid
- SMILES: O=C(COCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Biotin-PEG2-azide | 1910803-72-3 | 97.0% | 250 MG
Biotin-PEG2-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules containing DBCO or BCN groups. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Useful in cancer research and targeted therapy
Broadpharm Azido-PEG8-triethoxysilane, 1g | Formula: C28H58N4O12Si | Purity: 98%
Azido-PEG8-triethoxysilane is a short PEG linker featuring an azide, which is used in click chemistry with alkynes, and a triethoxysilane group, which may be used to retain a compound on silica surfaces such as those used in normal phase chromatography.
Medchemexpress LLC DSPE-PEG-alkyne | 85.0% | 2000 (Average) | 50 MG
DSPE-PEG-alkyne (MW 2000) is a PEG lipid designed to enhance the delivery efficiency and tissue specificity of poorly soluble drugs.
- Enhances delivery efficiency of poorly soluble drugs
- Improves tissue specificity
- Suitable for drug delivery research
Medchemexpress LLC H-151 alkyne (compound H-151-AL) | 2244892-03-1 | 95.1% | 275.30 g/mol | C17H13N3O | 10 MG
H-151 Alkyne is an alkyne-labeled derivative of H-151 that functions as a selective STING (Stimulator of Interferon Genes) inhibitor for research use. It is provided as a purified small molecule intended for biochemical and cell-based assays to probe STING-mediated signaling and related autoinflammatory or autoimmune disease mechanisms.
- Selective STING inhibition suitable for pathway studies.
- Alkyne handle enables click chemistry labeling and probe conjugation.
- Suitable for biochemical and cellular assays.
- High purity (95.1%) for reproducible results.
- Molecular weight 275.30 g/mol and formula C17H13N3O.
Medchemexpress LLC Propargyl-PEG4-O-C1-NHS ester | 1161883-51-7 | 25 MG
Propargyl-PEG4-O-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It also functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Enables selective degradation of target proteins
Medchemexpress LLC Biotin-PEG6-Mal | 1808990-66-0 | 99.0% | C31H51N5O11S | 50 MG
Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs selectively degrade target proteins by utilizing the ubiquitin-proteasome system
Medchemexpress LLC T-Boc-N-amido-PEG15-Br | 3012589-40-8 | 98.0% | C37H74BrNO17 | 25 MG
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
IPHASE PHARMA SERVICES LLC Rhesus Monkey Liver Microsomes,Male,0.5mL,20mg/mL
A major tool for metabolism stability study. Our liver microsomes products available in multi-species (human, monkey, beagle, rat, and mouse). We also offer customized products prepared from unconventional animal species, disease models, or animals of certain ages.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG24-CH2CH2COOH | 50 g | CAS 2170484-59-8 | MDL MFCD11041159
Fmoc-NH-PEG24-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2170484-59-8
- MDL: MFCD11041159
- InChIKey: NFOMZHGRFWXDGH-UHFFFAOYSA-N
- Molecular Weight: 1368.609
- Molecular Formula: C66H113NO28
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid
- SMILES: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)=O
Medchemexpress LLC Biotin-PEG2-acid | 1365655-89-5 | >97.0% | 403.49 g/mol | C17H29N3O6S | 50 MG
Biotin-PEG2-acid is a non-cleavable, two-unit polyethylene glycol (PEG) linker bearing a biotin affinity tag and a terminal carboxylic acid. It is supplied as an off-white to gray solid and is used to introduce hydrophilicity and a biotin handle in conjugation chemistries such as ADC and PROTAC synthesis.
- Non-cleavable two-unit PEG spacer improves solubility and linker flexibility.
- Terminal carboxylic acid enables standard conjugation chemistries.
- Biotin tag allows affinity capture and detection.
- High purity suitable for research applications.
- Available in multiple pack sizes including 50 MG for small-scale use.