Protein Modification Reagents
Medchemexpress LLC Propargyl-PEG4-O-C1-NHS ester | 1161883-51-7 | 500 MG
This compound is a PEG-based PROTAC linker used in the synthesis of PROTACs. It also functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Gly-gly-gly-PEG4-DBCO | 2353409-80-8 | 95.1% | 694.77 g/mol | C35H46N6O9 | 10 MG
Gly-Gly-Gly-PEG4-DBCO is a four-unit polyethylene glycol (PEG4) linker terminated with a dibenzocyclooctyne (DBCO) group, intended for click-chemistry bioconjugation such as antibody-drug conjugate synthesis. It reacts with azide-functionalized molecules via strain-promoted alkyne-azide cycloaddition (SPAAC), and is supplied as a powder suitable for laboratory conjugation workflows.
- Four-unit PEG linker with a DBCO functional group.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide partners.
- Suitable for site-specific bioconjugation and antibody-drug conjugate synthesis.
- Powder form with defined storage stability at low temperatures.
- Analytically characterized with reported purity for experimental reproducibility.
Medchemexpress LLC THP-PEG4-Pyrrolidine(N-Boc)-CH2OH | 2378261-80-2 | 95.0% | 25 MG
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker primarily used in the synthesis of PROTAC K-Ras Degrader-1. This compound serves as a crucial component for designing degraders that target specific proteins, utilizing the intracellular ubiquitin-proteasome system. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTAC K-Ras degrader-1
- Purity of 95.0%
- Molecular weight is 477.59
- Molecular formula is C23H43NO9
- Appearance is a colorless to light yellow liquid
- Store at -20°C under nitrogen
- Soluble in DMSO
eMolecules 17-(Bromoacetamido-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester | Broadpharm |873.961 | C40H77BrN2O13 | 98.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CBr | 250mg | 490840952
17-(Bromoacetamido-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester | Broadpharm |873.961 | C40H77BrN2O13 | 98.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CBr | 250mg | 490840952
eMolecules Broadpharm | Azido-PEG5-amine | 1g | 311074551 | BP-20590 | 98.000 | 516493-93-9 | MFCD16619318 | 306.363 | C12H26N4O5
Broadpharm | Azido-PEG5-amine | 1g | 311074551 | BP-20590 | 98.000 | 516493-93-9 | MFCD16619318 | 306.363 | C12H26N4O5
Bioworld D(+) Galactose, 250 g
An monosaccharidic aldo hexose potentially useful in aging studies. Specifications:High Purity GradeSpecific Rotation (2% water): 79 - 81°Appearance: White PowderBoiling Point : 410.8 °CDensity : 1.5 g/cm3HS Code : 29400090Melting Point: 168-170 °CRTECS Number: LW5490000
Medchemexpress LLC DSPE-PEG-DBCO | 99.9% | 2000 (average) | 25 MG
DSPE-PEG-DBCO (MW 2000) is a PEGylated phospholipid conjugate bearing a dibenzocyclooctyne (DBCO) group. It serves as a click-chemistry-capable lipid for incorporation into lipid nanoparticles or micelles and for rapid, copper-free conjugation to azide-containing molecules via strain-promoted alkyne-azide cycloaddition (SPAAC). Typical uses include nanoparticle formulation, surface PEGylation, and bioconjugation.
- PEGylated phospholipid with average molecular weight 2000.
- DBCO functional group enables copper-free SPAAC with azides.
- Suitable for lipid nanoparticle and micelle formulation.
- Facilitates bioconjugation and surface modification.
- High purity (reported 99.9%) for research applications.
Medchemexpress LLC APN-PEG5-VC-PAB-MMAE | 2252392-31-5 | 95.19% | 1577.90 | 5 MG
APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate that is part of INA03, a transferrin-competitive antibody-drug conjugate against CD71. It is for research use only.
- Drug-linker conjugate
- Part of INA03 (a transferrin-competitive antibody-drug conjugate against CD71)
Medchemexpress LLC Mal-PEG-mal (MW 2000) | 98.4% | 50 MG
Mal-PEG-mal (MW 2000) is a solid chemical compound primarily used as a PROTAC linker for laboratory applications and in the manufacturing of substances.
- Used as a PROTAC linker
- Suitable for laboratory chemical applications
- Suitable for substance manufacturing
- Solid appearance
- Store at -20°C, sealed, away from moisture
Medchemexpress LLC Biotin-PEG4-NHS ester | 459426-22-3 | 99.56% | C25H40N4O10S | 50 MG
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It can be used in the synthesis of PROTACs for research purposes only.
- Biotin-labeled, PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC m-PEG4-Hydrazide | 1449390-68-4 | >98% | C10H22N2O5 | 100 MG
M-PEG4-Hydrazide is a PEG-based PROTAC linker intended for research use only. It is utilized in the synthesis of PROTACs, which are Proteolysis-Targeting Chimeras. These chimeras consist of two ligands connected by a linker: one for an E3 ubiquitin ligase and another for the target protein. PROTACs employ the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Facilitates selective degradation of target proteins
- Intended for research use only