Protein Modification Reagents
eMolecules Mal-amido-PEG12-TFP ester | 1431295-77-0 | MFCD28505513 | 1g
Broadpharm | Mal-amido-PEG12-TFP ester | 1g | 550804214 | BP-22742 | 95.000 | 1431295-77-0 | MFCD28505513 | 916.911 | C40H60F4N2O17
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eMolecules Building Block Tool
Medchemexpress LLC Acid-PEG2-SS-PEG2-acid | 1807539-10-1 | 95.0% | 386.48 g/mol | C14H26O8S2 | 5 MG
Acid-PEG2-SS-PEG2-acid is a cleavable 4-unit polyethylene glycol (PEG) linker containing a central disulfide bond and terminal carboxylic acids, designed for use in antibody-drug conjugate (ADC) synthesis and bioconjugation. Supplied as a white to off-white solid for research use only.
- Cleavable disulfide bond enables intracellular release under reducing conditions.
- Terminal carboxyl groups allow amide coupling and conjugation chemistry.
- Four-unit PEG spacer improves solubility and reduces steric hindrance.
- High purity suitable for research applications.
- Solid, white to off-white appearance with recommended cold storage.
Medchemexpress LLC Endo-BCN-PEG4-PFP ester | 2904607-26-5 | 95.0% | C28H34F5NO8 | 10MG
endo-BCN-PEG4-PFP ester is a PEG-based bifunctional linker combining a strained alkyne (BCN) for strain-promoted alkyne-azide cycloaddition with a pentafluorophenyl (PFP) activated ester for efficient conjugation to primary amines. Supplied as an oil, it is designed for use in click chemistry, bioconjugation, and linker assembly in targeted degrader synthesis.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) without copper.
- PFP ester reacts efficiently with primary amines to form stable amide bonds.
- PEG4 spacer improves solubility and reduces steric hindrance.
- Suitable for bioconjugation and targeted degrader linker construction workflows.
- Stable when stored frozen; follow recommended storage conditions for longevity.
Medchemexpress LLC DSPE-pSar50 (DSPE-Polysarcosine50) | 3091879-29-4 | 99.91% | 4319.06 | 5 MG
DSPE-pSar50 (DSPE-Polysarcosine50) is a pSar-lipid derivative that serves as a hydrophilic alternative to PEG. It can be utilized in drug delivery research. The product is for research use only and not sold to patients.
- pSar-lipid derivative
- Hydrophilic alternative to PEG
- Utilized in drug delivery research
- For research use only
Cayman Chemical PomalIdomIde 1mg
An inhibitor of cereblon (IC50 = ~3 µM for the human recombinant CRBN-DDB1 complex); inhibits autoubiquitination of CRBN in HEK293T cells expressing CRBN; inhibits proliferation of U266 myeloma cells at 0.1-10 µM; reduces tumor growth in a H929 R10-1 lenalidomide-resistant mouse xenograft model at 3 mg/kg per day when used in combination with dexamethasone
![eMolecules 2112731-52-7 | N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203406.JPG-250.jpg)
eMolecules 2112731-52-7 | N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696
N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | 2112731-52-7 | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696
Medchemexpress LLC 4-Arm PEG-SCM MW 20 100mg
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]
STA Pharmaceutical Azide-PEG3-L-alanine-Fmoc | 50 g | CAS 2054345-69-4 | InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
Azide-PEG3-L-alanine-Fmoc is a Amino Acid reagent (Subcategory: Azido/Alkynyl AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2054345-69-4
- MDL: No data
- InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
- Molecular Weight: 484.509
- Molecular Formula: C24H28N4O7
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
- SMILES: O=C(N[C@H](COCCOCCOCCN=[N+]=[N-])C(O)=O)OCC1C2=C(C=CC=C2)C3=C1C=CC=C3
eMolecules 77544-68-4 | PEG3-Tos | Broadpharm | MFCD22574797 | 260.300 | C11H16O5S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCO | 10g | 550803903
PEG3-Tos | Broadpharm | 77544-68-4 | MFCD22574797 | 260.300 | C11H16O5S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCO | 10g | 550803903
Medchemexpress LLC Nh2-PEG6-CH2CH2COOH | 905954-28-1 | 353.41 | C15H31NO8 | 250 MG
NH2-PEG6-CH2CH2COOH is a cleavable six-unit polyethylene glycol (PEG) linker with an amino terminus and a terminal carboxyethyl group, intended for use in antibody-drug conjugate linker chemistry, PROTAC linker synthesis, and other bioconjugation applications.
- Cleavable six-unit PEG spacer provides hydrophilic separation between payload and targeting moiety.
- Amino terminus and carboxylic acid group enable diverse conjugation chemistries.
- Suitable for ADC and PROTAC linker development and general bioconjugation workflows.
- Available in small research pack sizes for laboratory use.
Medchemexpress LLC N3-PEG11-CH2CH2Br | 2098982-00-2 | MFCD32696701 | 99.8% | 634.56 g/mol | C24H48BrN3O11 | 50 MG
N3-PEG11-CH2CH2Br is a polyethylene glycol (PEG11) linker with an azide (N3) terminus and a bromide-functionalized ethylene spacer. It is a hydrophilic, viscous liquid used in bioconjugation and click-chemistry workflows to improve aqueous solubility and provide a reactive bromide handle for further modification.
- Azide-terminated PEG11 linker for click chemistry.
- Bromide-functionalized ethylene spacer provides a reactive handle.
- Hydrophilic PEG spacer increases solubility in aqueous media.
- High purity suitable for research applications.
- Recommended storage conditions maintain stability.
Medchemexpress LLC ERRα ligand-linker conjugates 1 | 98.8% | 601.42 | C24H20F9N3O5 | 5 MG
ERRα Ligand-linker conjugates 1 is a small-molecule ligand-linker intended as a building block for PROTAC design against estrogen-related receptor alpha (ERRα). It combines an ERRα-binding ligand with a PROTAC-compatible linker to facilitate recruitment of E3 ligases and construction of ERRα degraders. The material is supplied as a solid for medicinal chemistry and degradation studies.
- Designed for PROTAC synthesis
- Incorporates an ERRα-targeting ligand
- Compatible with common E3 ligase recruiters
- High purity suitable for research (98.8%)
- Supplied as a 5 mg solid
- Characterized: molecular weight 601.42, formula C24H20F9N3O5
Medchemexpress LLC Amino-PEG4-DOTA | 2090232-34-9 | 97.0% | 622.71 g/mol | C26H50N6O11 | 5mg
NH2-PEG4-DOTA is a bifunctional DOTA-type metal chelator NH2-PEG4-DOTA can be conjugated with Dextran for quantitative analysis in the presence of a highly luminescent complex NH2-PEG4-DOTA can also bind to radionuclides to prepare radionuclide drug conjugates (RDCs) RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy
Medchemexpress LLC Dbco-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 | 98.7% | 1672.01 | C88H126N12O20 | 10 MG
DBCO-PEG4-Val-Cit-PAB-MMAF is a cleavable ADC linker-payload conjugate that pairs a DBCO-functionalized PEG4 Val-Cit-PAB linker with the tubulin inhibitor MMAF. It is provided as a solid for use in antibody-drug conjugate synthesis and copper-free click chemistry (SPAAC) with azide-containing biomolecules. The Val-Cit-PAB spacer is designed for cathepsin-mediated cleavage to release the payload under lysosomal conditions.
- Cleavable Val-Cit-PAB spacer for enzymatic release.
- DBCO handle for copper-free click (SPAAC) conjugation.
- Hydrophilic PEG4 spacer improves solubility and flexibility.
- High reported purity suitable for research conjugation workflows.
- Available in small milligram pack sizes for lab-scale synthesis.