Protein Modification Reagents
Medchemexpress LLC Bis-PEG9-NHS ester 25mg | 1008402-79-6 | 708.71 | C30H48N2O17 | 25 MG
Bis-PEG9-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester reactive groups. It is provided as a white powder for research use in bioconjugation and linker assembly workflows, offering a hydrophilic, flexible spacer for coupling to primary amines in proteins and small molecules.
- Contains two NHS ester reactive groups for amine conjugation.
- PEG9 spacer increases aqueous solubility and conformational flexibility.
- Suitable for antibody-drug conjugate and PROTAC linker synthesis.
- High purity appropriate for research applications.
- Supplied in a small quantity format for small-scale reactions and method development.
Broadpharm Biotin-PEG2-azide | 1910803-72-3 | MFCD26142991 | 500mg
Biotin-PEG2-azide | Putity: 98% | MW: 400.5 | 1910803-72-3 | MFCD26142991 | 500mg
Broadpharm Amino-PEG2-acid | 791028-27-8 | MFCD20926377 | 1g
Amino-PEG2-acid | Putity: 98% | MW: 177.2 | 791028-27-8 | MFCD20926377 | 1g
Medchemexpress LLC Biotin-PEG1-NH2 | 811442-85-0 | 97.0% | 330.45 g/mol | C14H26N4O3S | 100 MG
Biotin-PEG1-NH2 is a cleavable one-unit polyethylene glycol (PEG) linker bearing a biotin tag and a terminal primary amine (-NH2), designed for use in the synthesis of antibody-drug conjugates (ADCs). Intended for research use only.
- Cleavable 1-unit PEG linker suitable for ADC synthesis.
- Biotin tag for affinity capture or detection.
- Terminal primary amine (-NH2) for conjugation chemistries.
- Purity 97.0%.
- Molecular weight 330.45 g/mol.
- CAS number 811442-85-0.
- Form: white to off-white solid; store protected from light; in solvent: -80°C (6 months), -20°C (1 month).
- Available packaging: 25 MG, 50 MG, 100 MG, 200 MG (quote), 500 MG (quote).
[C@@H](O)C(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)CO)-c2ccccc12 | 10mg | 445408913](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183529.JPG-250.jpg)
eMolecules LG-PEG10-click-DBCO-Oleic | Broadpharm |1407.701 | C70H114N6O23 | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=O)N1Cc2ccccc2-c2c(nnn2CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](O)[C@@H](O)C(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)CO)-c2ccccc12 | 10mg | 445408913
LG-PEG10-click-DBCO-Oleic | Broadpharm |1407.701 | C70H114N6O23 | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=O)N1Cc2ccccc2-c2c(nnn2CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](O)[C@@H](O)C(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)CO)-c2ccccc12 | 10mg | 445408913
Medchemexpress LLC Biotin-PEG6-Thalidomide | 2144775-48-2 | 98.3% | 791.91 | 5 MG
Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC DSPE-PEG-Maleimide | 1612754-08-1 | 99.9% | 2000 | 25 MG
DSPE-PEG-Maleimide is a functional lipid component and a thiol-reactive crosslinker. It undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD, making it suitable for research on drug delivery. In vitro, DSPE-PEG-Maleimide successfully conjugates with one thiolated RGD peptide via Michael addition at 4°C, pH 8 to form DSPE-PEG(2000)-RGD.
- Functional lipid component and thiol-reactive crosslinker
- Forms stable thioether bonds via Michael addition with thiol groups
- Applicable for research on drug delivery
- Conjugates with thiolated RGD peptides
Medchemexpress LLC m-PEG4-Tos 100mg | 62921-76-0 | 100 MG
m-PEG4-Tos is a tosylated polyethylene glycol (PEG4) reagent used as a PEG-based PROTAC linker and synthetic building block. It serves as a reactive tosylate for installing a PEG spacer in bifunctional degraders and related small-molecule conjugates. Supplied as a colorless to light yellow liquid at high purity, it is intended for research use and requires cold storage for long-term stability.
- Tosylated PEG4 spacer for efficient nucleophilic substitution.
- High purity (≥98.0% by NMR) suitable for synthesis.
- Colorless to light yellow liquid, simplifies handling and dispensing.
- Available in small synthetic quantities (e.g., 100 MG) for discovery work.
- Recommended cold storage to preserve stability in pure form or in solution.