Protein Modification Reagents
Medchemexpress LLC Dspe-peg-cho | 89.0% | 2000 (Average) | 50 MG
DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent featuring DSPE phospholipids and aldehyde groups. Its PEG linkers provide good hydrophilicity and water solubility. This reagent is commonly used to bind antibodies, peptides, or other ligands to the surface of liposomes and lipid-polyethylene glycol nanoparticles.
- Linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups.
- PEG linkers provide good hydrophilicity and water solubility.
- Used to bind antibodies, peptides, or other ligands to liposomes and lipid-polyethylene glycol nanoparticles.
- Can be used for drug delivery.
eMolecules 17-(amine-PEG9-ethylcarbamoyl)pentanoic t-butyl ester | Broadpharm |640.812 | C30H60N2O12 | 98.000 | CC(C)(C)OC(=O)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 250mg | 490840976
17-(amine-PEG9-ethylcarbamoyl)pentanoic t-butyl ester | Broadpharm |640.812 | C30H60N2O12 | 98.000 | CC(C)(C)OC(=O)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 250mg | 490840976
Cayman Chemical VH 032 LInker 2 50mg
A VHL Ligand 1 derivative; comprises the VHL ligand domain and PEG linker of the BET inhibitor-containing PROTACs MZ2 and MZP-55
Medchemexpress LLC (S,R,S)-ahpc-peg3-n3 | 1797406-80-4 | 99.7% | 645.77 g·mol⁻¹ | C30H43N7O7S | 25 MG
(S,R,S)-AHPC-PEG3-N3 is a VHL E3 ligase ligand-linker conjugate containing a three-unit polyethylene glycol (PEG3) spacer terminated with an azide group. It is designed as a PROTAC building block and for click chemistry conjugation to alkyne-bearing molecules.
- VHL ligand for recruiting von Hippel-Lindau E3 ligase.
- PEG3 spacer with a terminal azide suitable for copper-catalyzed azide-alkyne cycloaddition.
- Intended for PROTAC synthesis and small-molecule conjugation workflows.
- Molecular weight 645.77 g·mol⁻¹; formula C30H43N7O7S.
- High purity (>99.6% by LCMS), suitable for research applications.
- Storage: pure form -20°C (up to 3 years) or 4°C (up to 2 years).
eMolecules CBZ-aminooxy-PEG8-t-butyl ester | Broadpharm |647.759 | C31H53NO13 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCONC(=O)OCc1ccccc1 | 500mg | 550804549
CBZ-aminooxy-PEG8-t-butyl ester | Broadpharm |647.759 | C31H53NO13 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCONC(=O)OCc1ccccc1 | 500mg | 550804549
Medchemexpress LLC m-PEG4-Hydrazide | 1449390-68-4 | >98% | C10H22N2O5 | 250 MG
m-PEG4-Hydrazide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker, with one ligand for an E3 ubiquitin ligase and the other for the target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- For research use only
STA Pharmaceutical Fmoc-NH-PEG8-CH2COOH | 25 g | CAS 868594-52-9 | MDL MFCD27635163
Fmoc-NH-PEG8-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 868594-52-9
- MDL: MFCD27635163
- InChIKey: JRLUSGRARXJCNA-UHFFFAOYSA-N
- Molecular Weight: 649.734
- Molecular Formula: C33H47NO12
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules 557756-85-1 | Fmoc-PEG4-Propionic acid | AA Blocks LLC | MFCD06656472 | 487.549 | C26H33NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 410171202
Fmoc-PEG4-Propionic acid | AA Blocks LLC | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 410171202
Medchemexpress LLC DBCO-PEG4-DBCO | 2182601-68-7 | 97.4% | 1 G
DBCO-PEG4-DBCO is a PEG-based PROTAC linker used in the synthesis of PROTACs. It also functions as a cleavable ADC linker for synthesizing antibody-drug conjugates (ADCs) and is a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- PEG-based PROTAC linker
- Cleavable ADC linker
- Click chemistry reagent
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
eMolecules 125274-16-0 | Tr-PEG5 | Broadpharm | MFCD22574816 | 436.548 | C27H32O5 | 98.000 | OCCOCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1 | 1g | 112541223
Tr-PEG5 | Broadpharm | 125274-16-0 | MFCD22574816 | 436.548 | C27H32O5 | 98.000 | OCCOCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1 | 1g | 112541223
Medchemexpress LLC DBCO-PEG4-C2-acid | 1537170-85-6 | 99.2% | 250 MG
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent with a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs, which contain two different ligands connected by a linker (one for an E3 ubiquitin ligase and one for the target protein), utilize the intracellular ubiquitin-proteasome system for selective target protein degradation.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains a DBCO group
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide groups in molecules
Cayman Chemical dPE-PEG 2000 Cynur 500ug
A PEGylated form of DSPE; has been used in the generation of LNPs for the delivery of miRNA in vitro; LNPs containing DSPE-PEG(2000) cyanur, encapsulating let-7a miRNA, and conjugated to ephrin-A1 reduce the proliferation and colony formation and size of NCI H2081, NCI 5380, and A549 cancer cells, as well as reduce migration of NCI 5380 cells in a wound healing assay
STA Pharmaceutical Fmoc-N-amido-PEG-9-COOH | 1 g | CAS 1191064-81-9 | MDL MFCD28385470
Fmoc-N-amido-PEG-9-COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1191064-81-9
- MDL: MFCD28385470
- InChIKey: NEESTRVILHNOJT-UHFFFAOYSA-N
- Molecular Weight: 707.814
- Molecular Formula: C36H53NO13
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules 1807521-05-6 | Fmoc-PEG1-NHS ester | Broadpharm | MFCD28142469 | 452.463 | C24H24N2O7 | 98.000 | O=C(CCOCCNC(=O)OCC1c2ccccc2-c2ccccc12)ON1C(=O)CCC1=O | 1g | 263744717
Fmoc-PEG1-NHS ester | Broadpharm | 1807521-05-6 | MFCD28142469 | 452.463 | C24H24N2O7 | 98.000 | O=C(CCOCCNC(=O)OCC1c2ccccc2-c2ccccc12)ON1C(=O)CCC1=O | 1g | 263744717