Protein Modification Reagents
eMolecules 18-(Amine-PEG3-ethylcarbamoyl)heptadecanoic-t-butyl ester | Broadpharm |544.818 | C30H60N2O6 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCN | 100mg | 784454994
18-(Amine-PEG3-ethylcarbamoyl)heptadecanoic-t-butyl ester | Broadpharm |544.818 | C30H60N2O6 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCN | 100mg | 784454994
TARGETMOL CHEMICALS INC Biotin-PEG4-Amide-C6-Azide 2
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis. Purity 99.19%
STA Pharmaceutical Fmoc-NH-PEG5-CH2COOH | 5 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC DBCO-PEG6-NHS ester | 95.99% | 737.79 | 25 MG
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions, to form covalent bonds. It also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Reacts specifically with primary amines via NHS ester
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- Suitable for covalent bond formation
- Useful in click chemistry reactions
Medchemexpress LLC Nhpi-peg4-c2-nhs ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 | C23H28N2O11 | 50 MG
NHPI-PEG4-C2-NHS ester is an NHS-activated PEGylated linker reagent used in the synthesis of antibody-drug conjugates (ADCs). The molecule provides an activated ester for efficient coupling to primary amines and a PEG4 spacer that improves solubility and linker flexibility, supplied as a viscous liquid with high purity for research applications.
- Activated NHS ester for rapid conjugation to primary amines.
- Peg4 spacer improves aqueous solubility and linker flexibility.
- Suitable for construction of antibody-drug conjugates.
- High purity, viscous liquid form appropriate for research use.
- Store at -20°C in pure form; stability is reduced in solvent.
Medchemexpress LLC DSPE-PEG-alkyne | 85.0% | 2000 | 5 MG
DSPE-PEG-alkyne (MW 2000) is a PEG lipid.
- Can improve the delivery efficiency of poorly soluble drugs.
- Can improve the tissue specificity of poorly soluble drugs.
- Can be used in drug delivery research.
Medchemexpress LLC Mal-amido-PEG2-C2-acid | 756525-98-1 | 99.8% | 328.32 | 1 G
Mal-amido-PEG2-C2-acid is a PROTAC linker that is PEG-based and can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only and is not sold to patients.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
eMolecules 1807518-63-3 | BROMO-PEG2-CH2CO2TBU | AstaTech | MFCD28122957 | 283.162 | C10H19BrO4 | 95.000 | CC(C)(C)OC(=O)COCCOCCBr | 1g | 487923071
BROMO-PEG2-CH2CO2TBU | AstaTech | 1807518-63-3 | MFCD28122957 | 283.162 | C10H19BrO4 | 95.000 | CC(C)(C)OC(=O)COCCOCCBr | 1g | 487923071
Medchemexpress LLC Endo-BCN-PEG2-C2-NHS ester | 2243565-12-8 | 95.0% | 450.48 | 100 MG
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
![eMolecules 2112731-95-8 | N-(Azido-PEG3)-N-Boc-PEG4-acid | Broadpharm | MFCD30723226 | 566.649 | C24H46N4O11 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283675](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203403.JPG-250.jpg)
eMolecules 2112731-95-8 | N-(Azido-PEG3)-N-Boc-PEG4-acid | Broadpharm | MFCD30723226 | 566.649 | C24H46N4O11 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283675
N-(Azido-PEG3)-N-Boc-PEG4-acid | Broadpharm | 2112731-95-8 | MFCD30723226 | 566.649 | C24H46N4O11 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283675
Medchemexpress LLC Bromoacetamido-PEG5-DOTA | 2353410-19-0 | 98.02% | C30H55BrN6O13 | 25 MG
Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker crucial for synthesizing PROTACs. These molecules employ the intracellular ubiquitin-proteasome system to selectively degrade target proteins by linking an E3 ubiquitin ligase ligand with a target protein ligand. It appears as a white to off-white oil and is exclusively for research purposes.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Appears as an oil
- Color ranges from white to off-white
- Exclusively for research use
Biotium Insulin(E2-E3), CF594 conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Medchemexpress LLC P5(PEG24)-VC-PAB-exatecan | 2928571-43-9 | 99.74% | 2105.28 | 5 MG
P5(PEG24)-VC-PAB-Exatecan (LP5) is a drug-linker conjugate that combines a potent DNA Topoisomerase I inhibitor, Exatecan, with a P5(PEG24)-VC-PAB linker to form an antibody-drug conjugate (ADC). It is intended for tumor research.
- Drug-linker conjugate for ADC
- Composed of a potent DNA Topoisomerase I inhibitor exatecan
- Can be used for the research of tumor
- For research use only
Medchemexpress LLC Azido-PEG5-CH2CO2H | 217180-81-9 | MFCD31561141 | 98.9% | 321.33 g/mol | C12H23N3O7 | 25 MG
Azido-PEG5-CH2CO2H is an azide-functional polyethylene glycol (PEG) linker containing five ethylene glycol units, used as a cleavable spacer for bioconjugation. It is commonly applied in antibody-drug conjugate and PROTAC linker synthesis, and as a reagent for click chemistry (CuAAC and SPAAC).
- Azide-functional group for click chemistry (CuAAC and SPAAC).
- Five-unit PEG spacer provides hydrophilicity and flexibility.
- Cleavable carboxylic acid terminus suitable for conjugation strategies.
- High reported purity (~98.9%).
- Molecular weight ~321.33 g/mol; formula C12H23N3O7.
- Available in small research quantities (e.g., 25 mg).