Cytokines and Receptors Reagents and Kits
STEMCELL Technologies Human Recombinant IL-9, Size: 1000 µg
Interleukin 9 (IL-9) has pleiotropic functions in the immune system and signals through its specific IL-9 receptor (IL-9R) (Renauld et al.). IL-9/IL-9R signaling pathway mainly targets the downstream activation of JAK/STAT (janus kinase/signal transducer and activator of transcription) and subsequent phosphorylation cascades initiated by multiple kinases including IRS–PI3K–PKB (insulin receptor substrate, phosphatidyl-inositol 3-kinases, protein kinase-B) and ERK (Knoops & Renauld; Fontaine et al.). IL-9 has been shown to have a role in Th1/Th17-mediated inflammation and in regulatory T cell responses (Singh et al.; Goswami & Kaplan). IL-9/IL-9R signaling pathway represents a novel endogenous anti-apoptotic mechanism for cortical neurons (Fontaine et al.). IL-9 secreting T cells, termed Th9 cells, contribute to both effective immunity and immunopathological disease, and have been shown to have a role in the treatment of allergic and autoimmune disease (Kaplan et al.).
STEMCELL Technologies Human Recombinant IL-1 alpha, Size: 1000 µg
Interleukin 1 alpha (IL-1α) is a member of the IL-1 family and a dual-function cytokine. Both the unprocessed precursor and a processed IL-1α protein signal through IL-1 receptor type 1 (IL-1R1). Various cells, including keratinocytes, thymic epithelium, hepatocytes, endothelial cells, fibroblasts, and the epithelial cells of mucous membranes, have high levels of intracellular IL-1α precursor. The precursor is also expressed on the surface of monocytes and B lymphocytes (Netea et al.). IL-1α recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation (Cohen et al.; Rider et al.). During hypoxia, IL-1α contributes to angiogenesis (Carmi et al.). Studies in mice show that IL-1α is produced by microglia-like cells after ischemic brain injury, which contributes to the inflammation (Luheshi et al.).
STEMCELL Technologies Human Recombinant MCP-1 (CCL2), Size: 20 µg
Use monocyte chemotactic protein-1 (MCP-1) to activate signal transduction pathways that lead to monocyte transmigration (Sozzani et al. J Immunol, 1994). MCP-1, also known as CCL2, is primarily induced by platelet-derived growth factor gene (Cochran et al. Cell, 1983). MCP-1 plays a role in neurogenesis, neuroprotection, and neurotransmission and has implications in different neurological disorders (Conductier et al. J Neuroimmunol, 2010). MCP-1 is produced by a variety of cell types, including fibroblasts, endothelial, epithelial, monocytic, and microglial cells (Deshmane et al. J Interferon Cytokine Res, 2009). Human recombinant MCP-1 from STEMCELL comes lyophilized with ≥ 95% purity; specific activity EC50 ≤ 100 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: DIA, Differentiation-inducing factor, HILDA, Human interleukin in DA cells, Leukemia inhibitory factor, MCAF, Melanoma-derived LPL inhibitor, MLPLI, Monocyte chemoattractant protein 1.
![AG Scientific Inc Cellulase [Onozuka R-10] 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00081559-C-2745-5GM.JPG-250.jpg)
AG Scientific Inc Cellulase [Onozuka R-10] 5 G
Cellulase [Onozuka R-10] is derived from Trichoderma Viride. Cellulase R-10 is a multi-enzymatic system consisting of various enzymes, including cellulase, hemicellulase, pectinase and protease.Cellulase R-10 is typically used in association with macerozyme R-10 in the decomposition of plant cell walls to produce protoplasts.
Biotium Interleukin 10 IL10 Immunoregulation Marker IL102651R Biotin conjugate 0.1mgmL
Interleukin 10 IL10 Immunoregulation Marker IL102651R Biotin conjugate 0.1mgmL
Bioworld HUMAN INTERFERON-BETA 1B (R
HUMAN INTERFERON-BETA 1B (RECOMBINANT): Recombinant Human Interferon-beta 1b Source: E.Coli Background: One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-strand...
Bioworld HUMAN INTERLEUKIN-10 CHO (
HUMAN INTERLEUKIN-10, CHO (RECOMBINANT): Recombinant Human Interleukin-10 (IL-10) Source: CHO Background: Interleukin-10 is produced by murine T-cells following their stimulation by lectins. The main source for B-cell-derived Interle...
Bioworld HUMAN INTERLEUKIN-7 (RECOMB
HUMAN INTERLEUKIN-7 (RECOMBINANT): Recombinant Human Interleukin-7 (IL-7) Source: E.Coli Background :Interleukin 7 (IL-7), which is constitutively produced particularly by stromal cells from the bone marrow and thymus, plays a crucia...
Bioworld MOUSE INTERLEUKIN-2 (RECOMB
MOUSE INTERLEUKIN-2 (RECOMBINANT): Recombinant Murine Interleukin-2 Source: E.Coli Description: Recombinant Murine IL-2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids and having a molecu...
Bioworld MOUSE INTERLEUKIN-4 (RECOMB
MOUSE INTERLEUKIN-4 (RECOMBINANT): Recombinant Murine Interleukin-4 (IL-4) Source: E.Coli Description: Recombinant Mouse IL-4 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids and having a ...
Bioworld MOUSE INTERLEUKIN-7 (RECOMB
MOUSE INTERLEUKIN-7 (RECOMBINANT): Recombinant Mouse Interleukin-3 Source: E.Coli Background : Interleukin 7 (IL-7), which is constitutively produced particularly by stromal cells from the bone marrow and thymus, plays a crucial role...
Bioworld PORCINE INTERLEUKIN-1 ALPHA
PORCINE INTERLEUKIN-1 ALPHA (RECOMBINANT): Recombinant Porcine Interleukin-1 alpha Source: E.Coli Background : A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their r...
Bioworld PORCINE INTERLEUKIN-1 BETA
PORCINE INTERLEUKIN-1 BETA (RECOMBINANT): Recombinant Porcine Interleukin-1 beta Source: E.Coli Background : Interleukin-1 is a 12-stranded beta-sheet structure as both the heparin binding growth factors and the Kunitz-type soybean t...
Bioworld RAT MONOCYTE CHEMOTACTIC PR
RAT MONOCYTE CHEMOTACTIC PROTEIN-1 (CCL2), (RECOMBINANT): Recombinant Rat Monocyte Chemotactic Protein-1 (CCL2)- MCP-1 Source:E.Coli Description : Recombinant Rat MCP-1 produced in E.Coli is a non-glycosylated, Polypeptide chain cont...
Biolegend LEGENDplexTM NHP IL-12 p40
LEGENDplex™ NHP IL-12 (p40) Capture Bead B2, 13X Reactivity: Non-Human Primate; Apps: Multiplex - Component; Size: 100 tests (270 uL)