Toxins
Bioworld HUMAN BETAINE-HOMOCYSTEINE
HUMAN BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (RECOMBINANT): Synonyms: BHMT, Betaine Homocysteine S-Methyltransferase 1, BHMT1. Introduction: Betaine-homocysteine methyltransferase (BHMT) is a cytosolic enzyme that catalyzes the conversi...
Bioworld HUMAN BETAINE-HOMOCYSTEINE
HUMAN BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (RECOMBINANT): Synonyms: BHMT, Betaine Homocysteine S-Methyltransferase 1, BHMT1. Introduction: Betaine-homocysteine methyltransferase (BHMT) is a cytosolic enzyme that catalyzes the conversi...
Bioworld HUMAN BETAINE-HOMOCYSTEINE
HUMAN BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (RECOMBINANT): Synonyms: BHMT, Betaine Homocysteine S-Methyltransferase 1, BHMT1. Introduction: Betaine-homocysteine methyltransferase (BHMT) is a cytosolic enzyme that catalyzes the conversi...
AdipoGen T-2 Toxin
Chemical. CAS 21259-20-1. Formula C24H34O9. MW 466.5. Isolated from fungus Fusarium tricinctum. Common trichothecene mycotoxin, which can infect grain crops causing alimentary toxic aleukia in humans and animals. Inhibits DNA and RNA synthesis in vivo and in vitro and can induce apoptosis. In vivo the compound rapidly metabolizes to HT-2 mycotoxin a major metabolite. Inhibits protein synthesis through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs. Interferes with the metabolism of membrane phospholipids and increases liver lipid peroxides. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in brain. Reactive oxygen species ROS inducer.
Cayman Chemical Gunylate Cyclase 1 subunIt 1ea
A potent agonist of GPR35 orphan receptors (EC50 79 nM in aBarrestin recruitment assay) induces GPR35 translocation from the plasma membrane to the cytoplasm (EC50 22 nM) increases ERK1/2 phosphorylation in a concentration-dependent manner in U20S cells expressing human GPR35a has antinociceptive effects in a mouse abdominal constriction model of visceral pain perception (ED50 40.5 mg/kg)
Cayman Chemical CytochalasIn A 10mg
Antgen Vtg purfed from Amercan allgator (A mssssppenss) Host mouse Cross-reactvty ( ) Amercan allgator (A mssssppenss) Vtg Applcatons WB and ELSA sotype gG1-K
Cayman Chemical DIphthRIa ToxoId from Coryn
An inhibitor of VEGFR2 (IC50 0 0027 M for the human receptor) selective for human VEGFR2 over mouse VEGFR2 and human VEGFR1 and VEGFR3 (IC50s 1 5 1 7 and 1 1 M respectively) as well as 40-fold selective over B-RAF RET and Tie2 inhibits VEGF-induced proliferation of HUVECs (IC50 0 01 nM) inhibits VEGF-induced increases in tissue weight and Tie2 levels in an angiogenesis chamber implant model in mice at 1 and 3 mg/kg per day inhibits primary tumor and metastasis growth in a B16 melanoma mouse model at 3 mg/kg per day
Cayman Chemical Adenylate Cyclase TYP 3 Poly
A triacylglycerol has been found in nasturtium seed oil dietary administration at 30 of fat calories in a 60 fat diet in combination with sunflowerseed oil induces severe cardiac lipidosis in rats after 1 week with severity decreasing by 24 weeks is a minor component of Lorenzos oil
Cayman Chemical GABAA RECPTR a1 SubunIt Pol
A mixture of farnesene isomers may contain trans-b-farnesene cis-a-farnesene trans-a-farnesene and bisabolene among others
Cayman Chemical CytochalasIn D 1mg
An essental fatty acd n the -3 seres an ester of the free acd that s less water soluble but more amenable for the formulaton of steardonate-contanng dets and detary supplements
Cayman Chemical ToxIn BClostrIdIM dIF 50ug
A naturally occurring phospholipid produced by cells upon inflammatory stimulation less potent than PAF C-16 and PAF C-18 in the induction of neutrophil chemotaxis but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration
Cayman Chemical T-2 ToxIn-13C24 1.2mL
An inhibitor of the interaction between PD-1 and PDL1 (IC50 1 4 nM in a HTRF assay) increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1 (EC50 276 nM in a reporter assay)