Ssm Spooky Toxin TFA is a compound found in *Scolopendra mutilans* that acts as a potent inhibitor of KCNQ (voltage-gated potassium channel family 7) channels. It has IC50s of 2.8 μM, 5.26 μM, and 0.1-0.3 M for Kv7.4, Kv1.3, and Shal channels, respectively. This toxin also inhibits cytokine generation by specifically targeting the KV1.3 channel in T cells and plays an essential role in the centipede's circulatory system.
- Found in *Scolopendra mutilans*
- Potently inhibits KCNQ channels
- Inhibits cytokine generation
- Plays an essential role in the centipede's circulatory system
- Molecular weight: 6017.84 (free base)
- Purity: 99.09%
- Appearance: Solid, white to off-white
- Soluble in DMSO (100 mg/mL, requires ultrasonic)
- Powder storage: 2 years at -80°C, 1 year at -20°C (sealed, away from moisture)
- In solvent storage: 6 months at -80°C, 1 month at -20°C (sealed, away from moisture)