Toxins
List Biological Laboratories Inc Anthrax Edema Factor (EF), Recombinant, Mutant S447N from B. anthracis, 0.5 mg
Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development projects! Three proteins are collectively known as anthrax toxin: protective antigen (PA, 83 kDa), lethal factor (LF, 90 kDa) and edema factor (EF, 89 kDa). These proteins play a key role in the pathogenesis of anthrax. EF and LF have enzymatic functions associated with their carboxyl terminals, but require PA to achieve their biological effects. Edema factoris a calmodulin-dependent adenylate cyclase.19 After cell entry, EF is activated when complexed with calmodulin, creating excess amounts of cellular cyclic-AMP. The increase in cyclic-AMP upsets water homeostasis and disrupts the intracellular signaling pathways. It is responsible for the swelling in cutaneous anthrax infections. Edema factor is produced recombinantly in the native host. This mutant has a Ser to Asn substitution located at position 447 decreasing adenylatecyclase activity
Medchemexpress LLC HY-Y0304 50mg Medchemexpress, Dibutyl phthalate CAS:84-74-2 Purity:>98%
Medchemexpress, HY-Y0304 50mg Dibutyl phthalate CAS:84-74-2 Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications [1] . May cause toxicity and adverse neurobehavioral effects [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical ToxIn A from ClostrIdIM dIF
Specificity MouseExcitation max 565540498 nmEmission max 578 nmUses Flow cytometry Fluorescence microscopy
Cayman Chemical GABAA RECPTR a1 SubunIt Pol
A mixture of farnesene isomers may contain trans-b-farnesene cis-a-farnesene trans-a-farnesene and bisabolene among others
Bioss Cl. Difficile
Cl Difficile Primary Antibody Unconjugated Host Species Mouse Target Species Clonality Monoclonal Applications ELISA Concentration 100 g/ml Size 100 ug Storage Buffer PBS (pH 7 2) with 0 1% azide
Cayman Chemical Werner Syndrome RecQ Helicase
An antagonist of yoda1-activated Piezo1 (IC50 1.3 UM in HEK293 cells expressing the human receptor) selective for yoda1-actived Piezo1 over constituitively active Piezo1 TRPV4 and TRPC4 at 10 UM reduces the percentage of cells with yoda1-induced extracellular phosphatidylserine exposure in RBCs isolated from patients with sickle cell anemia at 10 UM inhibits yoda1-induced relaxation of isolated mouse aortic rings at 10 UM
Bioss Shiga toxin
Shiga toxin Primary Antibody Unconjugated Host Species Mouse Target Species Clonality Monoclonal Applications ELISA Concentration 100 g/ml Size 100 ug Storage Buffer PBS (pH 7 2) with 0 1% azide
Medchemexpress LLC HY-100309 2mg Medchemexpress, 9-amino-CPT CAS:91421-43-1 Purity:>98%
Medchemexpress, HY-100309 2mg 9-amino-CPT CAS:91421-43-1 9-amino-CPT (9-amino-20(S)-camptothecin) is a topoisomerase I inhibitor with potent anticancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Bioworld HUMAN BETAINE-HOMOCYSTEINE
HUMAN BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (RECOMBINANT): Synonyms: BHMT, Betaine Homocysteine S-Methyltransferase 1, BHMT1. Introduction: Betaine-homocysteine methyltransferase (BHMT) is a cytosolic enzyme that catalyzes the conversi...
Medchemexpress LLC HY-15739 100mg , Ansamitocin P-3 Antibiotic C 15003P3;Maytansinol butyrate;C15003P3 CAS:66584-72-3 Purity:98%
Medchemexpress, HY-15739 100mg Ansamitocin P-3 Antibiotic C 15003P3;Maytansinol butyrate;C15003P3 CAS:66584-72-3 Formula:C32H43ClN2O9 Microtubule Purity:98% Ansamitocin P-3 is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-16059 5mg Medchemexpress, Arglabin CAS:84692-91-1 Purity:>98%
Medchemexpress, HY-16059 5mg Arglabin CAS:84692-91-1 Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities. The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N1440 5mg Medchemexpress, Koumine CAS:1358-76-5 Purity:>98%
Medchemexpress, HY-N1440 5mg Koumine CAS:1358-76-5 Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells [1] . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities [3] , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0370 1g Medchemexpress, Bergapten CAS:484-20-8 Purity:>98%
Medchemexpress, HY-N0370 1g Bergapten CAS:484-20-8 Bergapten is a natural anti-inflammatory and anti-tumor agent isolated from bergamot essential oil, other citrus essential oils and grapefruit juice. Bergapten is inhibitory towards mouse and human CYP isoforms. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0596 5mg Medchemexpress, Panaxadiol CAS:19666-76-3 Purity:>98%
Medchemexpress, HY-N0596 5mg Panaxadiol CAS:19666-76-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.