Toxins
Cayman Chemical WRnr Syndrome rcQ Helcase 25mg
An inhibitor of WRN (IC50 = 100 nM in an enzyme activity assay); selectively inhibits WRN over BLM, RecQ1, and RecQ5 (IC50s = >100 µM for all in enzyme activity assays) and the growth of SW480 cells with unstable microsatellites over CAL-33 cells with stable microsatellites (GI50s = of 0.04 and >10 µM, respectively); induces proteosomal degradation of WRN in RKO cells at 0.75-10 µM; induces cell cycle arrest at the G2 phase in HCT116 cells at 10 µM; increases the levels of γH2AX and p21 and the levels of phosphorylated ATR, Chk2, and ATM, markers of DNA damage, in HCT116 and LS411N cells at 1 or 5 µM; decreases tumor volume without reducing body weight in a SW480 mouse xenograft model at 40, 60, or 120 mg/kg per day
Cayman Chemical HT-2 ToxIn-13C22 1.2mL
An internal standard for the quantification of HT-2 toxin by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Cephalomannine >=97% (HPLC), solid | 71610-00-9 | MFCD01075131 | 1MG
Cephalomannine >=97% (HPLC), solid | Purity: >=97% (HPLC) | Mol Wt: 831.9 | 71610-00-9 | MFCD01075131 | 1MG
Sigma Aldrich Fine Chemicals Biosciences Cephalomannine >=97% (HPLC), solid | 71610-00-9 | MFCD01075131 | 5MG
Cephalomannine >=97% (HPLC), solid | Purity: >=97% (HPLC) | Mol Wt: 831.9 | 71610-00-9 | MFCD01075131 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Arctiin phyproof(R) Reference Substance | 20362-31-6 | MFCD00870630 | 10MG
Arctiin phyproof(R) Reference Substance | Purity: >=98.0% (HPLC) | Mol Wt: 534.55 | 20362-31-6 | MFCD00870630 | 10MG
Sigma Aldrich Fine Chemicals Biosciences (-)-Arctigenin >=95% (LC/MS-ELSD) | 7770-78-7 | MFCD00870597 | 1MG
(-)-Arctigenin >=95% (LC/MS-ELSD) | Purity: >=95% (LC/MS-ELSD) | Mol Wt: 372.41 | 7770-78-7 | MFCD00870597 | 1MG
Sigma Aldrich Fine Chemicals Biosciences Alantolactone >=98% (HPLC) | 546-43-0 | MFCD00274568 | 25MG
Alantolactone >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 232.32 | 546-43-0 | MFCD00274568 | 25MG
Enzo Life Sciences Cylindrospermopsin (100µg). CAS: 143545-90-8
Tricyclic alkaloid hepatotoxin. Exhibits a completely different mechanism of toxicity than microcystins. Protein synthesis inhibitor. Might be carcinogenic. Inhibits pyrimidine nucleotide synthesis. Purity: ≥95% (HPLC). Solubility: Soluble in water, methanol or DMSO. Long Term Storage: -20°C.
Medchemexpress LLC HY-N0166 50mg Medchemexpress, Gramine CAS:87-52-5 Purity:>98%
Medchemexpress, HY-N0166 50mg Gramine CAS:87-52-5 Gramine (Donaxine) is a natural alkaloid isolated from giant reed [2] , acts as an active adiponectin receptor (AdipoR) agonist, with IC 50 s of 3.2 and 4.2 µM for AdipoR2 and AdipoR1, respectively [1] . Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist [2] . Gramine (Donaxine) has anti-tumor, anti-viral and anti-inflammatory properties [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.