General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Phospho-p53 (Ser15) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-p53 (Ser15) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Phospho and Total protein blocking reagent, 2 ml
HTRF Phospho and Total protein blocking reagent, 2 ml
Cayman Chemical Adipolysis Assay Kit, 1 ea
Cayman's Adipolysis Assay Kit provides a complete assay for studying the lipolysis of triglycerides, from the differentiation of adipocyte-like cells to the quantitation of released glycerol. 3T3-L1 cells are differentiated using a common adipogenesis induction procedure to accumulate lipid droplets, and isoproterenol is included as a positive control for release of glycerol from triglycerides. Free glycerol in the cell culture medium is measured by incubation with glycerol kinase, glycerol phosphate oxidase, and horseradish peroxidase in the presence of a colorimetric substrate to generate a chromophore detectable at 540 nm. The amount of glycerol release is correlated with both the amount of stored triglyceride and the degree of lipolysis, making this kit useful for investigators screening compounds affecting either lipid storage or metabolism. The Adipolysis Assay Kit provides enough reagents to assay one 96-well plate of.
Eurofins Discoverx PathHunter Human TORC1 (CRTC1) Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human TORC1 (CRTC1) Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure CRTC/CREB pathway activation via nuclear translocation of TORC1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human IL-8 (CXCR2) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human IL-8 (CXCR2) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human STAT3 Pathway Reporter Cell-Based Assay Kit (HepG2)
The PathHunter Human STAT3 Pathway Reporter Stable Cell Line Assay (HepG2) measures induced expression levels of a tagged reporter protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
AURORA BIOLABS LLC Kras Q61H Nucleotide Exchange Assay Kit,100 rxn
KRAS is a small GTPase in the RAS protein family that plays a critical role in regulating cell signaling pathways involved in proliferation, differentiation, and survival. KRAS cycles between an inactive GDP-bound state and an active GTP-bound state, and activation occurs through nucleotide exchange from GDP to GTP. Mutations such as KRAS Q61H are frequently associated with human cancers and contribute to abnormal signaling and uncontrolled cell growth. The KRAS Q61H Nucleotide Exchange Assay is a TR-FRET–based assay designed to quantitatively monitor nucleotide exchange activity of KRAS Q61H. The assay detects changes in fluorescence resonance energy transfer generated during nucleotide exchange, enabling measurement of KRAS activation and evaluation of compounds that modulate KRAS signaling for cancer research and drug discovery applications.
TRIBIOSCIENCE INC Lactic Lactate Fluorometric Assay 100 Tests
Tribioscience’s Lactate Fluorometric Assay Kit is a simple, sensitive, and fast assay that measures the total amount of L-Lactate in biological samples. Lactate is oxidized by lactate oxidase to pyruvate and hydrogen peroxide. Horseradish peroxidase (HRP) catalyzes the reaction between hydrogen peroxide and the specific probe to yield a final product measured by the fluorometric method at Ex/Em=530/590 nm.
Eurofins Discoverx PathHunter Human IL-7 (IL7R/IL2RG) Dimerization Cell-Based Assay Kit (DLD1)
The PathHunter Human IL-7 (IL7R/IL2RG) Stable Cell Line Dimerization Assay (DLD1) measures ligand-induced dimerization of IL7R/IL2RG. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Human IL-22R 2 ASY
The Meso Scale Discovery R-PLEX Human IL-22Ralpha2 Assay is a multiplex immunoassay that measures IL-22Ralpha2 in human serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements The assay can be multiplexed with other R-PLEX assays to analyze multiple biomarkers simultaneously This allows efficient and accurate quantification of IL-22Ralpha2 levels alongside other immune response markers With a testing time of just 3 5 hours this assay enables rapid profiling of IL-22Ralpha2
Eurofins Discoverx PathHunter Human RANK/IkB Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human RANK IkB Stable Cell Line Functional Kinase Assay (U2OS) measures pathway activation-induced degradation of IκB target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPA3 (EDG7) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human LPA3 (EDG7) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDG7 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx InCELL Hunter eXpress HEK 293 BRD3(1,2) Bromodomain Assay, 10-plate Kit. (96-0038E1CP7L)
The InCELL Hunter eXpress HEK 293 BRD3(1,2) Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of BRD3(1,2) via detection of BRD3(1,2) levels. This product uses EFC technology. The cell line included overexpresses BRD3(1,2) target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human SDF-1 alpha (CXCR4) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human SDF-1 alpha (CXCR4) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR4 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.