General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GLP1R Total GPCR Internalization Assay, 2-Plate Kit. (93-1075E3CP5M)
The PathHunter GLP1R Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of GLP1R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged GLP1R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the GLP1R receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Hampton Research CRYSTALHARP PLATE (SWIS 1EACR
HR3-188/CrystalHarp Plate (Swissci) - each. Please note items from this supplier are non-returnable.
Revvity Health Sciences Inc HTRF FLAG Detection Kit, 500 Assay Points
HTRF FLAG Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter Human MC5R β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MC5R β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MC5R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-17E (IL17RA/IL17RB) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-17E (IL17RA/IL17RB) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL17RA and IL17RB. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MR Nuclear Receptor Stable Cell Line Protein Interaction Assay (CHO-K1) contains a stable clonal cell line used to measure MR nuclear hormone receptor activation via nuclear translocation. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-7 (IL7R/IL2RG) Signaling Reporter Cell-Based Assay Kit (REH)
The PathHunter Human IL-7 (IL7R/IL2RG) Signaling STAT5 Reporter Stable Cell Line Assay (REH) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC). This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CDC25A Degradation Cell-Based Assay Kit (NCI-H460)
The PathHunter Human CDC25A Degradation Stable Cell Line Assay (NCI-H460) measures pathway activation-induced degradation of CDC25A target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AVPR1B Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human AVPR1B Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure AVPR1B (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human NF-kB Pathway Reporter Cell-Based Assay Kit (HEK 293)
The PathHunter NF-kB Pathway Reporter Stable Cell Line Assay (HEK 293) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human ADORA2B (A2B) Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADORA2B (A2B) Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADORA2B (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CDC25A Degradation Cell-Based Assay Kit (U2OS)
The PathHunter Human CDC25A Degradation Stable Cell Line Assay (U2OS) measures pathway activation-induced degradation of CDC25A target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.