General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Perforin-1 Detection Kit, 500 Assay Points
HTRF Human Perforin-1 Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress mUTR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0525E2MCP0L)
The PathHunter mUTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. urotensin II) based activation of mUTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mUTR2 and EA-tagged β-Arrestin-2. Activation of mUTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Total AKT1 Detection Kit, 500 Assay Points
HTRF Human Total AKT1 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF GTP / Gi protein Binding Kit, 20,000 Assay Points
HTRF GTP / Gi protein Binding Kit, 20,000 Assay Points
Eurofins Discoverx cAMP Hunter eXpress AGTRL1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0147E2CP2L)
The cAMP Hunter AGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of AGTRL1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type AGTRL1, a naturally Gi/Go coupled GPCR. Upon activation of AGTRL1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human GPR148 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR148 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR148 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
BioVendor, LLC Sircol; Dye & Dye Release Reagents (2 x 110 ml, 2 x 150 ml). CONTAINS: Sircol; Dye Reagent (2 x 110 ml) AND Sircol™ Dye Release Reagents (2 x 150 ml). Biocolor Item # S1500
Sircol; Dye & Dye Release Reagents (2 x 110 ml, 2 x 150 ml). CONTAINS: Sircol; Dye Reagent (2 x 110 ml) AND Sircol™ Dye Release Reagents (2 x 150 ml). Sircol™ Collagen Assay components. Biocolor Item # S1500
Eurofins Discoverx PathHunter eXpress CMKLR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0313E2CP0L)
The PathHunter CMKLR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. chemerin) based activation of CMKLR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CMKLR1 and EA-tagged β-Arrestin-2. Activation of CMKLR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Indigo Biosciences INDIGO BIOSCIENCES INC Assay, FGFR1c/α-Klotho, Endocrine FGF Signaling, 1x 384-well
This product is an assay for Endocrine FGF Signaling.
- Uses proprietary human cells engineered to provide constitutive expression of Human Fibroblast Growth Factor Receptor 1, isoform 1 and Human Fibroblast Growth Factor Receptor 2, isoform 1.
- Incorporates a luciferase reporter gene functionally linked to tandem NFAT consensus response element sequences.
- Provides an all-inclusive cell-based reporter assay system.
- Includes Reporter Cells, optimized culture medium, heparin-supplemented culture medium, FGF-Acidic (physiological paracrine activator of FGFR1/2), Luciferase Detection Reagents, and a cell culture-ready assay plate.
- Kit materials are sufficient to perform assays in a single 384-well assay plate.
- Cryopreserved mammalian cells are provided and require storage at -80°C until rapid-thaw.
- Intended for research purposes only.
Revvity Health Sciences Inc HTRF Phospho-NDRG1 (Thr346) Detection Kit, 10,000 Assay Points
HTRF Phospho-NDRG1 (Thr346) Detection Kit, 10,000 Assay Points
Eurofins Discoverx BEVACIZUMAB BIOASSAY HS, 2-PLA
PathHunter Bevacizumab Bioassay HS Kit, 2-Plate. (93-0996Y1-00165).
ILEX LIFE SCIENCES LLC BLYSCAN SGAG ISO/CONC REAGENTS
Biocolor Blyscan Glycosaminoglycan (sGAG) Isolation & Concentration Pack (100 samples). DESCRIPTION: Isolation & Concentration reagents for use with Blyscan Glycosaminoglycan Assay. Blyscan Glycosaminoglycan Assay is a quantitative colorimetric dye-binding method for analysis of sulfated proteoglycans and glycosaminoglycans (sGAG). It can be used to measure total sGAG content and can also to determine the O- and N-sulfated GAG ratio within test samples. The assay uses 1,9-dimethylmethylene blue dye employed under conditions that provide a specific label for the sulfated polysaccharide component of proteoglycans or the protein free sulfated glycosaminoglycan chains. APPLICATIONS: Cell culture derived material, soluble sGAGs from fluids (ex. synovial fluid, urine), fibrous and hyaline cartilages, tissues (ex. arteries, heart, lung, skin, tumors). Soluble sGAGs may be assayed directly, solid materials will require a preliminary papain extraction.
Abcam Histone Deacetylase (HDAC) Activity Assay Kit (Fluorometric)
Histone Deacetylase (HDAC) Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress AGTR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0312E2CP0L)
The PathHunter AGTR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. angiotensin II) based activation of AGTR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTR1 and EA-tagged β-Arrestin-2. Activation of AGTR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Insulin Lispro Bioassay Kit, 10pl. (93-0466Y3-00010)
The PathHunter Insulin Lispro Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses insulin or insulin lispro based activation of INSRb RTK receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged INSRb and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.