General Cell Based Assays
Revvity Health Sciences Inc HTRF Human α-SMA Detection Kit, 100,000 Assay Points
HTRF Human α-SMA Detection Kit, 100,000 Assay Points
Eurofins Discoverx PathHunter eXpress GPR173 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0380E2ACP1L)
The PathHunter GPR173 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR173 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR173 and EA-tagged β-Arrestin-2. Activation of GPR173 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR3 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0626E2CP1L)
The PathHunter GPR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF pAb Anti-Mouse IgG Eu-Conjugate, 5,000 Assay Points
HTRF pAb Anti-Mouse IgG Eu-Conjugate, 5,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-AKT1/2/3 (Thr308) Control Lysate
HTRF Human Phospho-AKT1/2/3 (Thr308) Control Lysate
Revvity Health Sciences Inc HTRF Mouse IL-1β Detection Kit, 10,000 Assay Points
HTRF Mouse IL-1β Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter Human FGFR3/FGFR3 Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human FGFR3/FGFR3 Dimerization Stable Cell Line Assay (U2OS) measures ligand-induced dimerization of FGFR3/FGFR3. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human SSTR2 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human SSTR2 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure SSTR2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Human & Mouse Total FOXO1 Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Total FOXO1 Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-SMAD3 (Ser423/425) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-SMAD3 (Ser423/425) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Tag-Lite Adenosine A2A Receptor Red Antagonist Ligand, 5,000 Assay Points
HTRF Tag-Lite Adenosine A2A Receptor Red Antagonist Ligand, 5,000 Assay Points
Revvity Health Sciences Inc HTRF Human and Mouse Total Cereblon Detection Kit, 10,000 Assay Points
HTRF Human and Mouse Total Cereblon Detection Kit, 10,000 Assay Points
Cayman Chemical FFA asy Sample Buffer 1ea
A PROTAC that drives Cdk2 degradation selectively degrades Cdk2 (IC50 24 nM) over seven additional CDKs at 500 nM but also degrades Aurora A kinase and IKZF1 at 250 nM reduces Cdk2 levels and increases the percentage of cells expressing CD11b a marker of differentiation in primary AML cells decreases proliferation without reducing the viability of as well as induces differentiation in primary HSCs
