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Specific assay kits designed measure the activation levels of small, active GTPases by isolating them via their specific downstream effectors. Kits employ molecular methods including pull-down affinity purification, electrophoresis, and western blotting.
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
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