Protein Purification
MilliporeSigma™ Calbiochem™ MPS1 Inhibitor, NMS-P715
The MPS1 Inhibitor, NMS-P715 controls the biological activity of MPS1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ α-Secretase Substrate II, Fluorogenic
An internally quenched fluorogenic peptide substrate containing the α-secretase cleavage site of β-Amyloid Precursor Protein (APP).
MilliporeSigma™ Calbiochem™ Nur77 LBD Antagonist, TMPA
A cell-permeable phenylacetate compound that blocks Nur77 (TR3) LKB1 nuclear-sequestering function by antagonizing against Nur77-LKB1 interaction via direct binding at the LKB1 LBD/ligand binding domain ( K d
MilliporeSigma™ Calbiochem™ PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A)
MilliporeSigma™ Calbiochem™ Ro106-9920
A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet
MilliporeSigma™ Calbiochem™ Glucose Transporter Inhibitor IV, WZB117
The Glucose Transporter Inhibitor IV, WZB117 controls the biological activity of Glucose Transporter.
MilliporeSigma™ Calbiochem™ PI 3-Kγ Inhibitor
The PI 3-Kγ Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Orai1/CRAC Blocker, Cpd5J-4
A non-toxic thiourea derivative that acts as a blocker of Orai1, the pore subunit of Ca2+-release-activated Ca2+ (CRAC) in T
MilliporeSigma™ Calbiochem™ SB 242084 Hydrochloride
A selective, brain-penetrant 5-HT2C receptor antagonist (pK
MilliporeSigma™ Calbiochem™ InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor
The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.
MilliporeSigma™ Calbiochem™ Cyclophilin A Inhibitor
The Cyclophilin A Inhibitor, also referenced under CAS 1186372-20-2, controls the biological activity of Cyclophilin A. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ (5Z)-Zeaenol, Curvularia sp.
A cell-permeable resorcylic acid lactone compound that may serve as a negative control for TAK1 (TGF-β-Activated Kinase-1) inhibition studies.
MilliporeSigma™ Calbiochem™ Tankyrase1/2 Inhibitor IV, JW55
The Tankyrase1/2 Inhibitor IV, JW55 controls the biological activity of Tankyrase1/2. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ PD 98059
PD 98059, CAS 167869-21-8, is a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK). Inhibits MAP Kinase activation and subsequent phosphorylation of MAP Kinase substrates.