Protein Purification
MilliporeSigma™ Calbiochem™ U18666A
A cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol.
MilliporeSigma™ Calbiochem™ U0126
U0126, CAS 109511-58-2, is a potent and specific inhibitor of MEK1 (IC50 = 72 nM) and MEK2 (IC50 = 58 nM). The inhibition is noncompetitive with respect to both ATP and ERK.
MilliporeSigma™ Calbiochem™ Vinblastine Sulfate
Antitumor alkaloid drug.
MilliporeSigma™ Calbiochem™ TRPM4 inhibitor, 9-Phenanthrol
The TRPM4 inhibitor, 9-Phenanthrol, also referenced under CAS 484-17-3, controls the biological activity of TRPM4. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Wnt Antagonist I, IWR-1-endo
Wnt Antagonist I, IWR-1-endo, is a cell-permeable inhibitor of TNKS1/PARP5a (IC50 = 131 nM) & TNKS2/PARP5b (IC50≥ 56 nM). Suppress Wnt-stimulated transcription activity (IC50 = 180 nM).
MilliporeSigma™ Calbiochem™ PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A)
MilliporeSigma™ Calbiochem™ AG 1295
A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500nM) and PDGF-dependent DNA synthesis (IC50 = 2.5μM) in Swiss/3T3 cells.
MilliporeSigma™ Calbiochem™ SB 242084 Hydrochloride
A selective, brain-penetrant 5-HT2C receptor antagonist (pK
MilliporeSigma™ Calbiochem™ Phenylmethylsulfonyl Fluoride
Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.
MilliporeSigma™ Calbiochem™ PLD Inhibitor, FIPI
The PLD Inhibitor, FIPI controls the biological activity of PLD. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ PPACK, Dihydrochloride
PPACK, Dihydrochloride, CAS 142036-63-3, is an extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set III
Phosphatase Inhibitor Cocktail Set III is a ready to use cocktail of four phosphatase inhibitors for broad-spectrum inhibition of both serine/threonine and protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ InSolution™ Bisindolylmaleimide I
A 1mg/mL solution of Bisindolylmaleimide I (Cat. No. 203290) in anhydrous DMSO.
MilliporeSigma™ Calbiochem™ JHDM Inhibitor VIII, SD70
A cell-permeable, bioavailable, non-toxic 8-hydroxyquinolinyl based compound that binds to and colocalizes with androgen receptor (AR) at both ligand-dependent and independent transcriptional regulatory elements
Thermo Scientific™ CaptureSelect™ Human Fab-kappa Kinetics Biotin Conjugate
Thermo Scientific™ CaptureSelect™ Human Fab-kappa Kinetics Biotin Conjugate is a bi-functional ligand construct consisting of 2 different 13 kDa recombinant single domain antibody fragments (affinity ligands).