Protein Purification
MilliporeSigma™ Calbiochem™ Polo-like Kinase Inhibitor II, BTO-1
The Polo-like Kinase Inhibitor II, BTO-1, also referenced under CAS 40647-02-7, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SKF-525A, Hydrochloride
Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system.
MilliporeSigma™ Calbiochem™ RORα/γ Agonist, SR1078
The RORα/γ Agonist, SR1078 controls the biological activity of RORα/γ. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ CX546
A positive allosteric modulator selective for the AMPA receptors.
MilliporeSigma™ Calbiochem™ InSolution™ Cyclopamine, V. californicum
The InSolution™ Cyclopamine, V. californicum controls the biological activity of Sonic Hedgehog signaling pathway. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ PD 168077 Maleate
A selective D4 dopamine receptor agonist (Ki
MilliporeSigma™ Calbiochem™ p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5
The p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5 controls the biological activity of p75NTR. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ PD 174265
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 450 pM).
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set I
Phosphatase Inhibitor Cocktail Set I contains three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A.
MilliporeSigma™ Calbiochem™ Smoothened Agonist, SAG
A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM).
MilliporeSigma™ Calbiochem™ Tau Aggregation Inhibitor, ATPZ, Cpd16
A water soluble (32uM in water) BBB-permeable ATPZ (aminothienopyridazine) tau aggregation inhibitor
MilliporeSigma™ Calbiochem™ Shikonin
A naphthoquinone found in the Chinese herb Shiunko.
MilliporeSigma™ Calbiochem™ Sodium Orthovanadate
A broad spectrum potent inhibitor of protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor VI, S3I-201
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor I
The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.