Protein Purification
AdipoGen GITRL Soluble hrecHis
Protein. The extracellular domain of human GITRL aa 74-199 is fused at the C-terminus to a His-tag. Source HEK 293 cells. Endotoxin content <0.06EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in PBS. Purity >90% SDS-PAGE. GITRL Glucocorticoid-induced TNF receptor ligand is expressed on dendritic cells DC, monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues e.g. testis. GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
AdipoGen IL-33 mouse rec His
Protein. Mouse IL-33 aa 109-266 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Binds to mouse and human ST2. Purity >90% SDS-PAGE. Interleukin-33 IL-33 HF-NEV IL-1F11, a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 IL1R1 and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 MAPK3/ERK2 MAPK1, p38 MAPK14, and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis.
Cayman Chemical K-Ras G12C InhIbItr 9 5mg
An irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 µM for 24 hours in vitro
![ABclonal Technology [KO Validated] Glutathione Synthetase (GSS) Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000109035.jpg-250.jpg)
ABclonal Technology [KO Validated] Glutathione Synthetase (GSS) Rabbit pAb
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Tosoh Bioscience LLC TSKGEL OLIGODNA RP 4.6X150
Column, Reversed Phase Chromatography; Tosoh TSKgel OligoDNA RP; Media: Silica; Particle: 5 micrometer; Pore Size: 250 angstrom; 4.6mm I.D. x 15cm Length; Stainless Steel - Standard
Proteintech Group Inc GFP-Trap Magnetic Agarose, kit
The ChromoTek GFP-Trap Magnetic Agarose are affinity beads for IP of GFP-fusion proteins. It comprises a GFP Nanobody/ VHH coupled to magnetic agarose beads.
Proteintech Group Inc GFP-Trap Magnetic Agarose
The ChromoTek GFP-Trap Magnetic Agarose are affinity beads for IP of GFP-fusion proteins. It comprises a GFP Nanobody/ VHH coupled to magnetic agarose beads.
Hampton Research SLICE PH REAGENT #62 (F2)
HR2-070-62/Slice pH #62 (F2), 185 ml - 1.0 M HEPES pH 6.8. Please note items from this supplier are non-returnable.
Hampton Research SLICE PH REAGENT #31 (C7)
HR2-070-31/Slice pH #31 (C7), 185 ml - 1.0 M MES monohydrate pH 5.9. Please note items from this supplier are non-returnable.
Hampton Research SLICE PH REAGENT #23 (B11)
HR2-070-23/Slice pH #23 (B11), 185 ml - 1.0 M Succinic acid pH 6.0. Please note items from this supplier are non-returnable.
Cayman Chemical VEGFR2 KInase InhIbItr II 1mg
A reversible, cell-permeable inhibitor of VEGFR2’s kinase activity (IC50 = 70 nM); less potently inhibits PDGFRβ (IC50 = 920 nM); blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 µM, respectively)
Proteintech Group Inc GFP-Trap Magnetic Particles M-270
GFP-Trap Magnetic Particles M-270 for immunoprecipitation (IP) of GFP-tagged proteins. GFP-Trap Magnetic Particles M-270 is highly recommended, when very large proteins/complexes are investigated, and magnetic separation is needed for IP. It consists of a GFP VHH/ Nanobody coupled to Magnetic Particles M-270.
Proteintech Group Inc GFP-Trap Agarose, kit
GFP-Trap Agarose is an affinity resin for IP of GFP-fusion proteins. It consists of a GFP Nanobody/ VHH coupled to agarose beads. The ChromoTek GFP-Trap Agarose is a ready-to-use reagent.