Protein Purification
MilliporeSigma™ Calbiochem™ IRAP Inhibitor, HFI-419
A substrate competitive inhibitor of insulin-regulated aminopeptidase (IRAP) activity (Ki = 0.48 μM against 25 μM Leu-AMC).
MilliporeSigma™ Calbiochem™ Mcl-1 Inhibitor II
A cell-permeable hydroxynaphthalenylthioacetate that targets Mcl-1 BH3-binding groove and selectively competes against 8nM FITC-AHA-BIM142-161 for Mcl-1, but not Bcl-xL, binding (IC50 = 310nM vs >40μM; [Mcl-1] & [Bcl-x
MilliporeSigma™ Calbiochem™ Formyl Peptide Receptor-Like 1 Antagonist, WRW4
The Formyl Peptide Receptor-Like 1 Antagonist, WRW4 controls the biological activity of Formyl Peptide Receptor-Like 1.
MilliporeSigma™ Calbiochem™ InSolution™ Ginkgolic Acid (15:1)
A 25 mM (2 mg/231 μl) sterile-filtered solution of Ginkgolic Acid (15:1) in DMSO.
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor I
The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor VIII
The GSK-3β Inhibitor VIII, also referenced under CAS 487021-52-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Dkk-1 Inhibitor, WAY-262611, HCl
The Dkk-1 Inhibitor, WAY-262611 controls the biological activity of Dkk-1.
MilliporeSigma™ Calbiochem™ Wnt Synergist, QS11
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
MilliporeSigma™ Calbiochem™ cFMS Receptor Inhibitor IV
The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NS309
A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.
MilliporeSigma™ Calbiochem™ PAR-2 Agonist I
The PAR-2 Agonist I controls the biological activity of PAR-2. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ ERK Inhibitor
The ERK Inhibitor, also referenced under CAS 1049738-54-6, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ellagic Acid, Dihydrate
A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties.
MilliporeSigma™ Calbiochem™ Eicosapentaenoic Acid
Cell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity.
MilliporeSigma™ Calbiochem™ Fumitremorgin C, Aspergillus. fumigatus
A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity.