Protein Purification
MilliporeSigma™ Calbiochem™ LRRK2-IN-1
LRRK2-IN-1 primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor II
The γ-Secretase Inhibitor II controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ bpV(HOpic)
A potent phosphotyrosine phosphatase inhibitor.
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MilliporeSigma™ Calbiochem™ Nefazodone Hydrochloride
A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor
Grazoprevir, Thermo Scientific™
MilliporeSigma™ Calbiochem™ 2,3-Butanedione 2-Monoxime
An inhibitor of skeletal and cardiac muscle contraction.
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor IV
A cell-permeable indenopyrazole compound that displays potent antiproliferative properties in several human tumor cell lines (IC50 < 33
MilliporeSigma™ Calbiochem™ Bcl-xL BH44-23, Human, Cell-Permeable
A cell-permeable peptide that prevents apoptotic cell death by directly binding to the voltage-dependent anion channel (VDAC) and blocking its activity.
MilliporeSigma™ Calbiochem™ PI 3-K Inhibitor XXI, GDC-0941
A cell-permeable, potent, ATP-competitive inhibitor of class IA (IC50 = 3 nM/p110α, 33 nM/p110β, 3 nM/p110δ) and IB PI 3-kinases (IC50 = 75 nM/p110γ).
MilliporeSigma™ Calbiochem™ HDAC6 Inhibitor II, BRD9757
A cell-permeable, low molecular weight hydroxamate compound that acts as a potent histone deacetylase class IIb HDAC6-selective inhibitor (IC50 = 30nM), while inhibiting class I HDAC1/2/3/8 only at higher concentrations (IC50
MilliporeSigma™ Calbiochem™ Porcn Inhibitor II, C59
A cell-permeable pyridinylphenyl-acetamide that is much more potent than IWP-2 (Cat
MilliporeSigma™ Calbiochem™ SU1498
A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC50 = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.
MilliporeSigma™ Calbiochem™ PP2
PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC50 = 4, 5, 5, & 100 nM for p56lck, p59fynT, Hck, & Src, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ NF-κB Activation Inhibitor
The InSolution™ NF-κB Activation Inhibitor controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ IP6K Inhibitor
The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.