Protein Purification
MilliporeSigma™ Calbiochem™ InSolution™ β-Secretase Inhibitor IV
The InSolution™ β-Secretase Inhibitor, also referenced under CAS 797035-11-1, controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ L-745,870 Trihydrochloride
Selective D4 receptor antagonist with excellent brain penetrat
MilliporeSigma™ Calbiochem™ Splitomicin
A cell-permeable lactone derived from β-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC50 = 60 μM).
MilliporeSigma™ Calbiochem™ PNU-120596
A urea derivative that acts as a potent, selective, and reversible positive allosteric modulator for the α7 subtype of neural nicotinic acetylcholine receptors
MilliporeSigma™ Calbiochem™ Fn14 Antagonist, L524-0366
Specifically binds to the Fn14 surface (Kd = 7.12 mM) and suppresses TWEAK-induced glioma cell migration.
MilliporeSigma™ Calbiochem™ JNK Inhibitor II
JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC50 = 40 nM for JNK-1 & JNK-2 & 90 nM for JNK-3).
MilliporeSigma™ Calbiochem™ MMP-2 Inhibitor II
The MMP-2 Inhibitor II, also referenced under CAS 869577-51-5, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ PLD Inhibitor, FIPI
The PLD Inhibitor, FIPI controls the biological activity of PLD. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Isoproterenol, Hydrochloride
Phenethylamine derivative.
MilliporeSigma™ Calbiochem™ (5Z)-7-Oxozeaenol, Curvularia sp.
(5Z)-7-Oxozeaenol, CAS 66018-38-0, is a cell-permeable, highly potent, selective, irreversible, and ATP-competitive inhibitor of MAPKKK TAK1 activity (IC50 = 8 nM).
MilliporeSigma™ Calbiochem™ HMTase Inhibitor IV, UNC0638
The HMTase Inhibitor IV, UNC0638 controls the biological activity of HMTase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Oxidized ATP (oATP)
A 2',3'-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes
MilliporeSigma™ Calbiochem™ InSolution™ Batimastat
A Marimastat type of peptidyl hydroxamate-based inhibitor that potently inhibits a broad-spectrum of metalloproteinases
MilliporeSigma™ Calbiochem™ InSolution™ 5-Aza-2'-Deoxycytidine
A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines.
MilliporeSigma™ Calbiochem™ Flumazenil
A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200μg/kg/i