Protein Purification
Cytiva HiScreen™ IMAC Sepharose™ 6 Prepacked Fast Flow Columns
Designed for method optimization and parameter screening
MilliporeSigma™ Calbiochem™ Methotrexate
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppress
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XII, Torin2
A Torin1 (Cat
MilliporeSigma™ Calbiochem™ ML-7, Hydrochloride
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).
MilliporeSigma™ Calbiochem™ NF279
A suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB
MilliporeSigma™ Calbiochem™ Microcystin-LW, Microcystis aeruginosa
Analog of Microcystin-LR with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.
MilliporeSigma™ Calbiochem™ Mevastatin, Sodium Salt
Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.
MilliporeSigma™ Calbiochem™ MG-115
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
MilliporeSigma™ Calbiochem™ Nitric Oxide Synthase, Neuronal Inhibitor I
The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Pepstatin A, Synthetic
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
MilliporeSigma™ Calbiochem™ miR-372/3 Inhibitor, Neomycin-S
A cell-permeable neomycin derived artificial nucleobase conjugate. Inhibits the production of oncogenic miRNAs 372 (IC50 = 2.4 μM) by binding to pre-miRNAs and interrupts processing by Dicer.
MilliporeSigma™ Calbiochem™ ADP-HPD, Dihydrate, Ammonium Salt
ADP-HPD, Dihydrate is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
Thermo Scientific™ CaptureSelect™ C-tagXL Pre-packed Column
Thermo Scientific™ CaptureSelect™ C-tagXL Affinity Matrix is an improved version of CaptureSelect C-tag Affinity Matrix with a significantly increased binding capacity, offered here in pre-packed format.
MilliporeSigma™ Calbiochem™ Omeprazole
A cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor.