Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ SB 202190, Hydrochloride
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190.
MilliporeSigma™ Calbiochem™ D-Val-Phe-Lys Chloromethyl Ketone, Dihydrochloride
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
MilliporeSigma™ Calbiochem™ MICAL-2 Inhibitor II, CCG-203971
A cell-permeable, restricted form of CCG-1423 with enhanced potency (IC50 = 4.2 μM vs 16.6 μM for PC-3 cell migration), but reduced off-target toxicity.
MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
A potent and cell-permeable inhibitor of p38 MAP kinase
MilliporeSigma™ Calbiochem™ Pyruvate Kinase Activator
The Pyruvate Kinase Activator controls the biological activity of Pyruvate Kinase. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Cdk7 Inhibitor VIII, THZ1
A cell-permeable, non-toxic, phenylaminopyrimidinyl-acrylamide compound that acts as a highly potent, selective, ATP-site directed, and irreversible inhibitor of Cdk7 (IC50
MilliporeSigma™ Calbiochem™ Ubiquitin Isopeptidase Inhibitor I, G5
The Ubiquitin Isopeptidase Inhibitor I, G5, also referenced under CAS 108477-18-5, controls the biological activity of Ubiquitin Isopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ p-APMSF, Hydrochloride
Alternative to DFP and PMSF.
MilliporeSigma™ Calbiochem™ 1-Pyrrolidinecarbodithioic Acid, Ammonium Salt
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
MilliporeSigma™ Calbiochem™ InSolution™ JAK Inhibitor I
The InSolution™ JAK Inhibitor I, also referenced under CAS 457081-03-7, controls the biological activity of JAK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PI 3-Kα Inhibitor IV
The PI 3-Kα Inhibitor IV, also referenced under CAS 1188890-32-5, controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor IV
A cell-permeable indenopyrazole compound that displays potent antiproliferative properties in several human tumor cell lines (IC50 < 33
MilliporeSigma™ Calbiochem™ N-WASP-Inhibitor, 187-1
The N-WASP-Inhibitor, 187-1 controls the biological activity of neural Wiskott Aldrich syndrome protein (N-WASP). This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ SU11652
A cell-permeable pyrrole-indolinone compound that acts as a potent, reversible, and ATP-competitive tyrosine kinase receptor and angiogenic inhibitor.
MilliporeSigma™ Calbiochem™ SMER28
A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin and acts as an autophagy stimulator both in mammalian cultures