Protease Inhibitors and Phosphatase Inhibitors
Apexbio Technology LLC Deacetylase Inhibitor Cocktail (100 in 70% DMSO), 1ml x 50
maintain the acetylation state of proteins Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Cell Counting Kit-8 (CCK-8), 6X5ml (3000 tests)
Our product Cell Counting Kit-8 (CCK-8) provide a more convenient and sensitive method for the research of cell number determination and cell proliferationtotoxicity assay than previous ways. The kit utilizes a highly water-soluble tetrazolium salt, WST-8, which produces a water-soluble formazan dye upon reduction in the presence of an electron mediator. The amount of the formazan generated by dehydrogenases is directly in proportion to the numbers of living cells. The detection sensitivity by CCK-8 is higher than other tetrazolium salts such as MTT, XTT, MTS or WST-1. Other sizes are available. Please inqury us for quote.
Cayman Chemical PKR InhIbItr 5mg
Binds the ATP-binding site of PKR and blocks autophosphorylation (IC50 = 186-210 nM); protects neuroblastoma cells against cell damage triggered by ER stress; prevents phosphorylation of FADD, preventing apoptosis; reduces phosphorylation of PKR and eIF2α in the brain, enhancing long-term memory storage
Apexbio Technology LLC Protease Inhibitor Cocktail (EDTA-Free, 200X in DMSO), 1ml
Equivalent to Sigma P1860, for use in tissue culture media to prevent proteolytic degradation of secreted proteins. Other sizes are available. Please inqury us for quote.
Selleck Chemical LLC Crenolanib (CP-868596) 5mg 670220-88-9 ARO 002
Crenolanib (CP-868596, ARO 002) is a potent and selective inhibitor of PDGFR?/? with Kd of 2.1 nM/3.2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src. Crenolanib helps to induce mitophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
![Medchemexpress LLC Phenol, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]- | 1638-41-1 | MFCD00397032 | 99.0% | 456.94 g/mol | C12H4Cl6O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Phenol, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]- | 1638-41-1 | MFCD00397032 | 99.0% | 456.94 g/mol | C12H4Cl6O4S | 5 MG
p38 MAP Kinase Inhibitor IV is an ATP-competitive inhibitor selective for p38α and p38β MAPKs, used as a biochemical tool to probe p38 signaling. It has IC50 values of 0.13 μM (p38α) and 0.55 μM (p38β), and is supplied as a high-purity solid for research applications.
- ATP-competitive inhibitor with defined IC50 values for mechanistic studies.
- High purity (99.0%) for reliable biochemical and cellular assays.
- Solid powder form for convenient storage and handling.
- Recommended storage conditions provided to preserve stability.
- Molecular weight and formula supplied for analytical and formulation work.
Cayman Chemical PRMT4CARM1 InhIbItr 1mg
A selective inhibitor of PRMT4/CARM1 (IC50 = 7.1 µM); reduces the prostate-specific antigen promoter activity in human prostate cancer LNCaP cells
Sigma Aldrich Fine Chemicals Biosciences Pepstatin A | 26305-03-3 | | 10MG
Pepstatin A | Purity: 100,000 U/mg | Mol Wt: 685.89 | 26305-03-3 | | 10MG
Sigma Aldrich Fine Chemicals Biosciences Leupeptin | 103476-89-7 | MFCD00037012 | 25mg
Leupeptin | Purity: 90% | Mol Wt: 475.59 | 103476-89-7 | MFCD00037012 | 25mg
Gold Biotechnology Inc Pepstatin A 100 mg
Pepstatin A is a competitive, reversible aspartic protease inhibitor and inhibits proteases such as pepsin, chymosin, renin, HIV proteases, and cathepsins D and E. Peptstatin A is highly selective and is often used in a mixture with other enzyme inhibitors. In vitro studies have shown pepstatin A is the only aspartic acid inhibitor that exhibits inhibitory effects on HIV proteases.
Cayman Chemical NFKB ActIvatIon InHBTr II 25mg
An inhibitor of NF-κB activation; inhibits TNF-α-induced NF-κB activation in HT-1080 cells at 20 µM; inhibits TNF-α-induced expression of MMP-9 in HT-1080 cells; decreases TNF-α-induced migration of HT-1080 cells at 20 µM; inhibits IL-6 release induced by TNF-α from primary rat brain pericytes at 1, 5, and 10 µM; increases IL-8 secretion in HT-29 and Caco-2 cells at 5 µM in combination with glyoxal
Cayman Chemical ARK1 InhIbItr 10mg
An inhibitor of GRK2/βARK1 (IC50 = 126 µM); selective for GRK2/βARK1 over PKA at concentrations up to 1 mM; decreases systolic blood pressure in ob/ob and nicotinamide plus streptozotocin-induced mouse models of type 2 diabetes at 200 UG/kg; improves clonidine-induced relaxation of precontracted isolated aortic rings and improves glucose tolerance in the ob/ob mouse model; inhibits serotonin- or neurotensin-induced DIR in the rat ventral tegmental area in vitro
Cayman Chemical CathepsIn L InhIbItr 25mg
A potent cathepsin L inhibitor (IC50 = 0.85 nM); selective for cathepsin L over calpain II and cathepsin B (IC50s = 184, and 85.1 nM, respectively); trypanocidal against T. brucei (ED50 = 45 nM); completely suppresses osteoclastic pit formation on femur slices isolated from bovine cortical bone at a concentration of 1 μg/ml; inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner
Medchemexpress LLC Boc-Pro-prolinal | 86925-97-5 | MFCD00890691 | 98.3% | 296.36 g/mol | C15H24N2O4 | 5 MG
Prolyl endopeptidase inhibitor 1 (Boc-Pro-prolinal) is a small-molecule inhibitor of prolyl endopeptidase (PEP) used in biochemical and pharmacological research. It displays high affinity (Ki = 15 nM) and has reported anti-amnesic effects in preclinical studies. The compound is supplied as a solid and as DMSO stock solutions, with recommended storage at -20°C for solid material and -80°C for long-term solvent stocks.
- High potency against prolyl endopeptidase (Ki = 15 nM).
- High purity (98.34%).
- Available as solid and as DMSO stock solutions.
- Supplied in research-scale quantities suitable for in vitro and preclinical studies.
- Storage instructions provided for solid and solvent formats.
Selleck Chemical LLC JIB-04 20mg 199596-05-9 NSC 693627
JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D in cell-free assays, respectively. JIB?04 also induces cell apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.