Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PP1 Analog V, 2,3-DMB-PP1
A cell-permeable 3-MB-PP1 analog that is more effective than 3-MB-PP1 in inhibiting Syk
MilliporeSigma™ Calbiochem™ U0124
A useful negative control for MEK inhibitors U0125 and U0126.
MilliporeSigma™ Calbiochem™ TLR1/TLR2 Agonist II, CU-T12-9
A diphenyl substituted imidazole based compound that directly and selectively targets TLR1/2 and induces their dimerization and activates TLR1 and 2 signaling leading to NF-κB and AP-1 activation ( K D = 182 and 478 nM, respectively; EC50
MilliporeSigma™ Calbiochem™ AG 126
A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages.
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor II
The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ TGF-β RI Kinase Inhibitor II, RepSox
A cell-permeable, potent, selective, reversible, and ATP-competitive inhibitor of TGF-β type I receptor (ALK5; IC50 = 23 nM, 4nM and 18nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-β cellular assay in HepG2 cells, respectively)
MilliporeSigma™ Calbiochem™ PARP Inhibitor III, DPQ
The PARP Inhibitor III, DPQ, also referenced under CAS 129075-73-6, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor I
Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.
MilliporeSigma™ Calbiochem™ WRN Helicase Inhibitor, NSC 19630
The WRN Helicase Inhibitor, NSC 19630, also referenced under CAS 72835-26-8, controls the biological activity of WRN Helicase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ USP14 Inhibitor, IU1
The USP14 Inhibitor, IU1 controls the biological activity of USP14. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ BDK Inhibitor II, (S)-CPP
A cell-permeable inhibitor of mitochondrial branched-chain α-ketoacid dehydrogenase complex (BCKDC) regulatory kinase BDK (IC50 = 6.3 μM).
MilliporeSigma™ Calbiochem™ TMEM16A Activator, Eact
The TMEM16A Activator, Eact modulates the biological activity of TMEM16A. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ AMPK Signaling Activator XIII, ZLN005
Calbiochem AMPK Activator, CAS 4529-96-8, inhibits luciferase activity, and activates AMPK signaling.
MilliporeSigma™ Calbiochem™ Isoproterenol, Hydrochloride
Phenethylamine derivative.
MilliporeSigma™ Calbiochem™ HMTase Inhibitor IV, UNC0638
The HMTase Inhibitor IV, UNC0638 controls the biological activity of HMTase. This small molecule/inhibitor is primarily used for Cancer applications.