Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ WHI-P180
A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo.
MilliporeSigma™ Calbiochem™ PKCθ/δ Inhibitor
A cell-permeable pyridinecarbonitrile compound that acts as a potent, ATP-competitive (Ki = 79 nM, using PKCθ KD in coupled PK/LDH assays), and isozyme-selective PKCθ inhibitor (IC50 = 70nM) with much reduced potency against other novel PKCs (IC50
MilliporeSigma™ Calbiochem™ cPLA2α Inhibitor II, Pyrrophenone
A cell-permeable, highly potent, and reversible inhibitor of cytosolic phospholipase A2a (IC50 = 4.2 nM).
MilliporeSigma™ Calbiochem™ PI 3-Kα Inhibitor VIII
The PI 3-Kα Inhibitor VIII controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Granzyme B Substrate II, Fluorogenic
A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.
MilliporeSigma™ Calbiochem™ SKF-525A, Hydrochloride
Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system.
MilliporeSigma™ Calbiochem™ mTOR Kinase Inhibitor II, WYE-354
The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Epoxomicin, Synthetic
Epoxomicin, Synthetic, CAS 134381-21-8, is a potent, specific, and irreversible inhibitor of chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide hydrolyzing activities of the proteasome.
MilliporeSigma™ Calbiochem™ Ubiquitin E1 Inhibitor, PYR-41
The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Thrombin Receptor Agonist
The Thrombin Receptor Agonist, also referenced under CAS 137339-65-2, controls the biological activity of Thrombin Receptor. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Reboxetine Mesylate
A potent and selective inhibitor of noradrenalin uptake (Ki values ar
MilliporeSigma™ Calbiochem™ Ruthenium Red
A blocker of transmembrane Ca2+ fluxes (IC50 = 7 μM) that attenuates capsaicin-induced cation channel opening.
MilliporeSigma™ Calbiochem™ Granzyme B Inhibitor I
The Granzyme B Inhibitor I controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor Set I
The Caspase Inhibitor Set I controls the biological activity of Caspase-1. This collection of small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Pin1 Inhibitor, DTM
A cell permeable competitive inhibitor of Pin1 (EC50 = 4.1 μM, Ki = 50 nM).