Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor II, JSH-23
The NF-κB Activation Inhibitor II, JSH-23, also referenced under CAS 749886-87-1, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ mTOR Kinase Inhibitor II, WYE-354
The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NF023
A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go
MilliporeSigma™ Calbiochem™ MLKL Inhibitor, Necrosulfonamide
MLKL Inhibitor, Necrosulfonamide, CAS 432531-71-0, is a cell-permeable inhibitor that covalently modifies Cys88 and blocks human MLKL adaptor function.
MilliporeSigma™ Calbiochem™ Oridonin, R. rubescens
A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative and antiangiogenic properties.
MilliporeSigma™ Calbiochem™ TNF-α Inhibitor
The TNF-α Inhibitor, also referenced under CAS 1049741-03-8, controls the biological activity of TNF-α.
MilliporeSigma™ Calbiochem™ InSolution™ Trichostatin A, Streptomyces sp.
A potent and reversible inhibitor of histone deacetylase
MilliporeSigma™ Calbiochem™ Vacuolin-1
A cell-permeable triazine based compound that inhibits Ca
MilliporeSigma™ Calbiochem™ U-73343
A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
MilliporeSigma™ Calbiochem™ AG 1478
A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase.
MilliporeSigma™ Calbiochem™ V-ATPase Inhibitor, KM91104
A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 o
MilliporeSigma™ Calbiochem™ InSolution™ U0126
A potent and specific inhibitor of MEK1 and MEK2 .
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632
Y-27632A, CAS 146986-50-7, is a cell-permeable, reversible, inhibitor of Rho kinases (Ki = 140 nM for p160ROCK). Enhances survival & cloning efficiency of ESC without affecting their pluripotency.
MilliporeSigma™ Calbiochem™ Vincristine Sulfate, Apocynaceae sp.
Indole alkaloid that binds to tubulin, inhibiting formation of microtubules.
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).