Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 5-Nitro-2-(3-phenylpropylamino)benzoic Acid
Potent Cl- channel blocker (IC50 = 100 nM-100 μM), depending on channel subtype and assay method.
MilliporeSigma™ Calbiochem™ Necrostatin-1, Inactive Control
A cell-permeable N-demethylated thiohydantoin analog of Nec-1 that is devoid of anti-necroptotic properties and serves as a suitable inactive control.
MilliporeSigma™ Calbiochem™ NF-κB SN50M, Cell-Permeable Inactive Control Peptide
An inactive control for SN50 peptide.
MilliporeSigma™ Calbiochem™ Ruthenium Red
A blocker of transmembrane Ca2+ fluxes (IC50 = 7 μM) that attenuates capsaicin-induced cation channel opening.
MilliporeSigma™ Calbiochem™ RAD51-Stimulatory Compound-1, RS-1
A cell-permeable sulfonamido-benzamide-based allosteric regulator that stimulates DNA binding and recombinase activities of hRAD51 by locking hRAD51 in an active conformation without affecting its active site ATP hydrolysis.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase p300 Inhibitor, C646
Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket.
MilliporeSigma™ Calbiochem™ InSolution™ TAPI-2
A 10 mM (1 mg/241 μL) sterile-filtered solution of TAPI-2 in H2O.
MilliporeSigma™ Calbiochem™ Memantine Hydrochloride
Memantine Hydrochloride is a very potent, voltage-dependent, rapidly unbinding antagonist (calcium channel blocker) of NMDA receptors.
MilliporeSigma™ Calbiochem™ Myeloperoxidase Inhibitor-II
A 5-fluorotryptamine derivative that inhibits myeloperoxidase/MPO activity (IC50 = 18nM) via direct affinity interaction with enzyme active site heme pyrrole ring D, while exhibiting much reduced affinity toward serotonin reuptake transporter/SERT ( K i
MilliporeSigma™ Calbiochem™ InSolution™ JAK Inhibitor I
The InSolution™ JAK Inhibitor I, also referenced under CAS 457081-03-7, controls the biological activity of JAK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Integrin αvβ3 Antagonist, P11
The Integrin αvβ3 Antagonist, P11 controls the biological activity of Integrin αvβ3.
MilliporeSigma™ Calbiochem™ Spermidine, Trihydrochloride
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.