Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 1,2-Dioctanoyl-sn-glycerol
Cell-permeable activator of protein kinase C (PKC).
MilliporeSigma™ Calbiochem™ ODQ
A cell-permeable, potent and selective inhibitor of nitric oxide (NO)-sensitive guanylyl cyclase (IC50 = 20 nM).
MilliporeSigma™ Calbiochem™ 5-Nitro-2-(3-phenylpropylamino)benzoic Acid
Potent Cl- channel blocker (IC50 = 100 nM-100 μM), depending on channel subtype and assay method.
MilliporeSigma™ Calbiochem™ NS8593
An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels in a Ca2+-dependent manner.
MP Biomedicals™ Phosphatase Inhibitor Cocktail, 10X
This Phosphatase Inhibitor Cocktail is suitable for protein extraction from animal cells or tissue and can maintain protein phosphorylation.
MilliporeSigma™ Calbiochem™ TrkB Antagonist, ANA-12
A cell-permeable thiophene carboxymide derived compound that acts as a direct and selective antagonist of TrkB receptor
MilliporeSigma™ Calbiochem™ p-Aminophenylmercuric Acetate
An organomercurial agent used for the activation of latent MMPs in vitro.
MilliporeSigma™ Calbiochem™ Etomoxir
A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Potassium Salt
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
MilliporeSigma™ Calbiochem™ NDGA
A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 μM, and 30 μM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 μM).
MilliporeSigma™ Calbiochem™ InSolution™ MG-132 in EtOH, ≥95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor. Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex.
MilliporeSigma™ Calbiochem™ Nifedipine
Relatively selective blocker of L-type Ca2+ channels.
MilliporeSigma™ Calbiochem™ mTOR Kinase Inhibitor II, WYE-354
The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NF023
A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go
MilliporeSigma™ Calbiochem™ Oridonin, R. rubescens
A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative and antiangiogenic properties.