Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ β-Glycerophosphate, Disodium Salt, Pentahydrate
A phosphate group donor in matrix mineralization studies that acts as a protein phosphatase inhibitor.
MilliporeSigma™ Calbiochem™ Myeloperoxidase Inhibitor-II
A 5-fluorotryptamine derivative that inhibits myeloperoxidase/MPO activity (IC50 = 18nM) via direct affinity interaction with enzyme active site heme pyrrole ring D, while exhibiting much reduced affinity toward serotonin reuptake transporter/SERT ( K i
MilliporeSigma™ Calbiochem™ Granzyme B Substrate VIII, Colorimetric
A colorimetric substrate for granzyme B (kcat/Km = 6.6 x 104 M-1s-1).
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, Sodium Salt
Important intracellular second messenger implicated in the action of nitric oxide in many cell types.
MilliporeSigma™ Calbiochem™ 1,2-Dioctanoyl-sn-glycerol
Cell-permeable activator of protein kinase C (PKC).
MilliporeSigma™ Calbiochem™ Lavendustin A
A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase and p60c-src with little effect on protein kinase A or protein kinase C.
MilliporeSigma™ Calbiochem™ InSolution™ Nutlin-3, Racemic
A cell-permeable, potent, and selective MDM2 antagonist (IC50 = 90nM for Nutlin-3a and 13
MilliporeSigma™ Calbiochem™ MDM2 Antagonist, Nutlin-3, Racemic
The MDM2 Antagonist, Nutlin-3, Racemic, also referenced under CAS 548472-68-0, controls the biological activity of MDM2. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ MMP Inhibitor V
The MMP Inhibitor V, also referenced under CAS 223472-31-9, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Inhibitor II
The MMP-2/MMP-9 Inhibitor II, also referenced under CAS 193807-60-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ MAS 7
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.
MilliporeSigma™ Calbiochem™ Ibotenic Acid
A highly potent agonist of NMDA and mGlu receptors.
MilliporeSigma™ Calbiochem™ VEGF Inhibitor, V1
The VEGF Inhibitor, V1 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ W-13, Hydrochloride
A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 58 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 68 μM).
MilliporeSigma™ Calbiochem™ InSolution™ Lovastatin, Sodium Salt
Carboxylate form of Lovastatin that is active in whole cells and cell-free assays.