Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PDE4D Inhibitor, GEBR-7b
The PDE4D Inhibitor, GEBR-7b controls the biological activity of PDE4D. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Focal Adhesion Kinase Inhibitor III
A cell-permeable pyrazolobenzothiazinedioxide compound that targets and locks FAK in its inactive conformation, resulting in preincubation time-dependent inhibition in kinase assays and FAK autophosphorylation in human prostate cancer PC3M-luc cells (IC50
MilliporeSigma™ Calbiochem™ Diethyl Pyrocarbonate
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles.
MilliporeSigma™ Calbiochem™ Caspase-1 Substrate VI, Fluorogenic
Fluorogenic caspase-1 substrate.
MilliporeSigma™ Calbiochem™ BAY 11-7082
The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ MAS 7
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.
MilliporeSigma™ Calbiochem™ Rottlerin
Rottlerin, CAS 82-08-6, is a cell-permeable, reversible inhibitor of protein kinase C with greater selectivity for PKCδ(IC50= 3-6μM) and PKCθ. Has about 10-fold lower potency against other isozymes.
MilliporeSigma™ Calbiochem™ 1-β-D-Arabinofuranosylcytosine
Anticancer, antiviral agent that is especially effective against leukemias.
MilliporeSigma™ Calbiochem™ (-)-Blebbistatin
The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.
MilliporeSigma™ Calbiochem™ Autophagy Inhibitor IV, Cpd18
A cell-permeable 3-methyladenine (3-MA) derivative that acts as an autophagy inhibitor via the inhibition of class III PI3K, and without touching class I PI3K
MilliporeSigma™ Calbiochem™ PARP Inhibitor VI, NU1025
The PARP Inhibitor VI, NU1025, also referenced under CAS 90417-38-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ LIM Kinase Inhibitor I, LIMKi 3
The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor II, JSH-23
The NF-κB Activation Inhibitor II, JSH-23, also referenced under CAS 749886-87-1, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ PKCζ/ι Pseudosubstrate Inhibitor
The PKCζ/ι Pseudosubstrate Inhibitor controls the biological activity of PKCζ/ι. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Calpain Substrate II, Fluorogenic
Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2.