Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Neuronal Differentiation Inducer III
A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 μM) in various stem/progenitor cells.
MilliporeSigma™ Calbiochem™ DNA-PK Inhibitor V
The DNA-PK Inhibitor V, also referenced under CAS 404009-46-7, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ KN-93
A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370nM)
MilliporeSigma™ Calbiochem™ Resveratrol, Triacetyl
A cell-permeable triacetate resveratrol prodrug that is easily converted to resveratrol by esterase activity and exhibits similar bioactivity as resveratrol in cell cultures.
MilliporeSigma™ Calbiochem™ Cantharidic Acid
A potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
MilliporeSigma™ Calbiochem™ Splitomicin
A cell-permeable lactone derived from β-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC50 = 60 μM).
MilliporeSigma™ Calbiochem™ Ezh2 Inhibitor II, EI1
A cell-permeable indolocarboxamide compound
MilliporeSigma™ Calbiochem™ InSolution™ Aphidicolin
A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.
MilliporeSigma™ Calbiochem™ Lovastatin
Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
MilliporeSigma™ Calbiochem™ Celastrol, Celastrus scandens
A cell-permeable dienone-phenolic triterpene compound that exhibits antioxidant and anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor III
The TGF-β RI Kinase Inhibitor III, also referenced under CAS 356559-13-2, controls the biological activity of TGF-β RI Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ RAF Kinase Inhibitor VII
A cell-permeable imidazopyridinyl-urea compound that acts as a potent inhibitor against B-RafV600E activity (IC50 = 1nM) by targeting its ATP-binding pocket and the adjacent lipophilic allosteric site accessible only when the enzyme is in its inactive DFG-out confor
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor IV
β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1).
MilliporeSigma™ Calbiochem™ Kallikrein Substrate, Fluorogenic
Sensitive fluorogenic substrate for kallikreins.
MilliporeSigma™ Calbiochem™ Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac
The Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac controls the biological activity of Sialyltransferase.