Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ JNK Inhibitor II
The InSolution™ JNK Inhibitor II, also referenced under CAS 129-56-6, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Carboplatin
An analog of Cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.
MilliporeSigma™ Calbiochem™ Ro-20-1724
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ Amiloride, Hydrochloride
An inhibitor of angiogenesis.
MilliporeSigma™ Calbiochem™ Fn14 Antagonist, L524-0366
Specifically binds to the Fn14 surface (Kd = 7.12 mM) and suppresses TWEAK-induced glioma cell migration.
MilliporeSigma™ Calbiochem™ 3-Nitropropionic acid
A cell-permeable, irreversible inactivator (≈3 mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme.
MilliporeSigma™ Calbiochem™ Casein Kinase II Inhibitor I
The Casein Kinase II Inhibitor I, also referenced under CAS 17374-26-4, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ FPT Inhibitor II
The FPT Inhibitor II controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ Wortmannin
Wortmannin is a fungal metabolite that acts as a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase).
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor Set I
The Proteasome Inhibitor Set I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Midkine Inhibitor, iMDK
A cell-permeable imidazothiazolyl-chromenone compound that reduces cellular midkine/MDK protein level in H441 lung adenocarcinoma cells in a dose-dependent manner (by >90% in 48 h at 25nM) via a yet unidentified mechanism
MilliporeSigma™ Calbiochem™ Lovastatin
Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
MilliporeSigma™ Calbiochem™ Aurora Kinase/Cdk Inhibitor
The Aurora Kinase/Cdk Inhibitor, also referenced under CAS 443797-96-4, controls the biological activity of Aurora Kinase/Cdk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Trypsin Inhibitor, Soybean, High Activity
Trypsin Inhibitor, Soybean, High Activity, CAS 9035-81-8 is of the several protease inhibitors in soybeans. Inhibits trypsin in 1:1 stoichiometry.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor I
Z-VAD-FMK, CAS 187389-52-2, is a cell-permeable, irreversible, pan-caspase inhibitor.