Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A)
MilliporeSigma™ Calbiochem™ InSolution™ Foxo1 Inhibitor, AS1842856
A cell-permeable oxodihydroquinoline
MilliporeSigma™ Calbiochem™ Zonisamide
An antiepileptic agent that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels.
MilliporeSigma™ Calbiochem™ Withaferin A, Withania somnifera
A cell-permeable steroidal lactone that displays antitumor, anti-inflammatory, radiosensitizing, and immunosuppressive properties.
MilliporeSigma™ Calbiochem™ Flt-3 Inhibitor
The Flt-3 Inhibitor, also referenced under CAS 301305-73-7, controls the biological activity of Flt-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Src Inhibitor, PP1
The Src Inhibitor PP1, also referenced under CAS 172889-26-8, controls the biological activity of Src. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set II, Lyophilized
The Phosphatase Inhibitor Cocktail Set II, Lyophilized controls the activity of Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Nociceptin
Endogenous ligand for the opioid-like G-protein coupled receptor, ORL1 (Opioid Receptor-Like 1).
MilliporeSigma™ Calbiochem™ AICA-Riboside, 5'-Phosphate
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase).
MilliporeSigma™ Calbiochem™ PPACK, Dihydrochloride
PPACK, Dihydrochloride, CAS 142036-63-3, is an extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry.
MilliporeSigma™ Calbiochem™ TLR1/TLR2 Agonist II, CU-T12-9
A diphenyl substituted imidazole based compound that directly and selectively targets TLR1/2 and induces their dimerization and activates TLR1 and 2 signaling leading to NF-κB and AP-1 activation ( K D = 182 and 478 nM, respectively; EC50
MilliporeSigma™ Calbiochem™ Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride
A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki =
MilliporeSigma™ Calbiochem™ InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor
The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.
MilliporeSigma™ Calbiochem™ 2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor I, S32826
The Autotaxin Inhibitor I, S32826, also referenced under CAS 1103672-43-0, controls the biological activity of Autotaxin.